Diabetic retinopathy (DR) is an ocular complication of diabetes mellitus (DM). International
Diabetic Federations (IDF) estimates up to 629 million people with DM by the year 2045 …

Damage-associated molecular patterns (DAMPs) are endogenous danger molecules
released from the extracellular and intracellular space of damaged tissue or dead cells …

Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease (ESRD)
worldwide. SGLT2 inhibitors are clinically effective in halting DKD progression. However, the …

Recently, the leading cause of preventable blindness is diabetic retinopathy (DR). Although
there are several undiagnosed and non-treated cases of DR, accurate and adequate retinal …

The number of diabetic patients in Europe and world-wide is growing. Diabetes confers a 2-
fold higher risk for vascular disease. Lack of insulin production (Type 1 diabetes, T1D) or …

Diabetics are more vulnerable to SARS-CoV-2 neurological manifestations. The molecular
mechanisms of SARS-CoV-2-induced cerebrovascular dysfunction in diabetes are unclear …

Abstract Background Type 2 diabetes (T2D) is a complex metabolic ailment marked by a
global high prevalence and significant attention in primary healthcare settings due to its …

Small extracellular vesicles (sEVs) derived from the plasma have been increasingly
recognized as important vehicles of intercellular communication and potential sources of …

Purpose: Retinal neovascularization (RNV) is the leading cause of vision loss in diseases
like proliferative diabetic retinopathy (PDR). A significant failure rate of current treatments …

Glucose metabolism in neuronal tissue declines during neurodegenerative disorders in a
progressive, region-specific, and disease-specific manner. Studies have shown that …