The separation and segregation of newly replicated bacterial chromosomes can be
constrained by the formation of circular chromosome dimers caused by crossing over during …

As bacteria proliferate, DNA replication, chromosome segregation, cell wall synthesis, and
cytokinesis occur concomitantly and need to be tightly regulated and coordinated. Although …

Nisin is applied as a food preservative in processed foods and has the potential to be used
synergistically with antibiotics for treatment of patients infected by antibiotic-resistant …

The translocation of DNA during bacterial cytokinesis is mediated by the SpoIIIE/FtsK family
of proteins. These proteins ensure efficient chromosome segregation into sister cells by ATP …

Unregulated cell cycle progression may have lethal consequences and therefore, bacteria
have various mechanisms in place for the precise spatiotemporal control of cell cycle events …

Staphylococcus aureus is generally thought to divide in three alternating orthogonal planes
over three consecutive division cycles. Although this mode of division was proposed over …

Peptidoglycan is an essential component of the cell wall that protects bacteria from
environmental stress. A carefully coordinated biosynthesis of peptidoglycan during cell …

We have developed GmPcides from a peptidomimetic dihydrothiazolo ring-fused 2-pyridone
scaffold that has antimicrobial activities against a broad spectrum of Gram-positive …

Bacterial cell growth and division require temporal and spatial coordination of multiple
processes to ensure viability and morphogenesis. These mechanisms both determine and …

Productive bacterial cell division and survival of progeny requires tight coordination between
chromosome segregation and cell division to ensure equal partitioning of DNA. Unlike rod …