Resequencing and mutational analysis using oligonucleotide microarrays

JG Hacia - Nature genetics, 1999 - nature.com
Oligonucleotide microarray (DNA chip)–based hybridization analysis is a promising new
technology which potentially allows rapid and cost–effective screens for all possible …

Application of microarray technology in environmental and comparative physiology

AY Gracey, AR Cossins - Annual Review of Physiology, 2003 - annualreviews.org
▪ Abstract DNA microarray technology is revolutionizing many aspects of biological research,
allowing the expression of many thousands of gene transcripts to be monitored …

Massive parallel method for decoding DNA and RNA

J Ju, Z Li, JR Edwards, Y Itagaki - US Patent 6,664,079, 2003 - Google Patents
Chiu NH, Tang K., Yip P., Braun A., Koster H., Cantor CR, Mass spectrometry of Single-
Stranded restriction frag ments captured by an undigested complementary Sequence …

Parallel genotyping of human SNPs using generic high-density oligonucleotide tag arrays

JB Fan, X Chen, MK Halushka, A Berno… - Genome …, 2000 - genome.cshlp.org
Large scale human genetic studies require technologies for generating millions of
genotypes with relative ease but also at a reasonable cost and with high accuracy. We …

Massive parallel method for decoding DNA and RNA

J Ju, Z Li, JR Edwards, Y Itagaki - US Patent 7,345,159, 2008 - Google Patents
This invention provides methods for attaching a nucleic acid to a solid surface and for
sequencing nucleic acid by detecting the identity of each nucleotide analogue after the …

Colorimetric silver detection of DNA microarrays

I Alexandre, S Hamels, S Dufour, J Collet… - Analytical …, 2001 - Elsevier
Development of microarrays has revolutionized gene expression analysis and molecular
diagnosis through miniaturization and the multiparametric features. Critical factors affecting …

Combinatorial fluorescence energy transfer tags and their applications for multiplex genetic analyses

J Ju, Z Li, A Tong, JJ Russo - US Patent 6,627,748, 2003 - Google Patents
This invention provides a combinatorial fluorescence energy transfer tag which comprises a
plurality of fluorescent molecules, comprising one or more energy transfer donor and one or …

Multiplex genotyping using solid phase capturable dideoxynucleotides and mass spectrometry

J Ju - US Patent 7,074,597, 2006 - Google Patents
Benson, SC, Mathies, RA and GlaZer, AN (1993) Heterodimeric DNA-binding dyes designed
for energy transfer: stability and applications of the DNA complexes. Nucleic Acids Res. 21 …

Mutational analysis using oligonucleotide microarrays

JG Hacia, FS Collins - Journal of medical genetics, 1999 - jmg.bmj.com
The development of inexpensive high throughput methods to identify individual DNA
sequence differences is important to the future growth of medical genetics. This has become …

Photocleavable fluorescent nucleotides for DNA sequencing on chip constructed by site-specific coupling chemistry

J Ju - US Patent 7,622,279, 2009 - Google Patents
57 ABSTRACT Related US Application Data(57)(60) Provisional application No.
60/550,007, filed on Mar. This invention provides a method for determining the 3, 2004 …