Strategies for management of patients with, or at risk for, medication-related osteonecrosis of
the jaws (MRONJ)–formerly referred to as bisphosphonate-related osteonecrosis of the jaws …

Importance Multiple myeloma is a hematologic malignancy characterized by presence of
abnormal clonal plasma cells in the bone marrow, with potential for uncontrolled growth …

Since nuclear factor of κ‐light chain of enhancer‐activated B cells (NF‐κB) was discovered
in 1986, extraordinary efforts have been made to understand the function and regulating …

Osteoporosis is a global public health problem, with fractures contributing to significant
morbidity and mortality. Although postmenopausal osteoporosis is most common, up to 30 …

Highlights•The clinical course of advanced cancer for many patients with bone metastases
can be transformed through optimum multidisciplinary management.•Bone-targeted agents …

Osteocytes, former osteoblasts encapsulated by mineralized bone matrix, are far from being
passive and metabolically inactive bone cells. Instead, osteocytes are multifunctional and …

Skeletal complications caused by osteoporosis or bone metastases are associated with
considerable pain, increased mortality, and reduced quality of life. Furthermore, such events …

Prostate cancer (PCa) affects millions of men globally. Due to advances in understanding
genomic landscapes and biological functions, the treatment of PCa continues to improve …

The Medication-Related Osteonecrosis of Jaws (MRONJ) diagnosis process and its
prevention play a role of great and rising importance, not only on the Quality of Life (QoL) of …

Rheumatoid arthritis is a chronic autoimmune syndrome associated with several genetic,
epigenetic, and environmental factors affecting the articular joints contributing to cartilage …