Osteoarthritis (OA) is a degenerative and chronic joint disease characterized by clinical
symptoms and distortion of joint tissues. It primarily damages joint cartilage, causing pain …

Articular cartilage is susceptible to damage but hard to self-repair due to its avascular
nature. Traditional treatment methods are not able to produce satisfactory effects …

Bone marrow mesenchymal stem/stromal cells (BMSCs), which are known as multipotent
cells, are widely used in the treatment of various diseases via their self-renewable …

Objective Stem cells are considered to be one of the greatest potential treatments to cure
degenerative diseases. Stem cells injection for knee osteoarthritis is still a relatively new …

Osteoarthritis (OA) is a degenerative multifactorial disease with concomitant structural,
inflammatory, and metabolic changes that fluctuate in a temporal and patient-specific …

Abstract Background Extracellular vesicles (EVs) secreted by mesenchymal stem cells
(MSCs) may play a vital role in a variety of biological processes, including cartilage …

Background: Intra-articular injection of autologous culture-expanded adipose-derived
mesenchymal stem cells (ADMSCs) has introduced a promising treatment option for knee …

Background Mesenchymal stromal cell (MSC)-enriched products showed positive clinical
outcomes in regenerative medicine, where tissue restoration and inflammation control are …

Exosomes are nanosized vesicles (30–140 nm) of endocytic origin that play important roles
in regenerative medicine. They are derived from cell membranes during endocytic …

Purpose This review aimed to evaluate the efficacy of intra-articular injections of bone
marrow derived mesenchymal stem cells (BM-MSCs) for the treatment of knee osteoarthritis …