Recent breakthroughs in AI coupled with the rapid accumulation of protein sequence and
structure data have radically transformed computational protein design. New methods …

The entry of SARS-CoV-2 into host cells involves the interaction between the viral spike
protein and the human angiotensin-converting enzyme 2 (ACE2) receptor. Given that the …

Since the SARS-CoV-2 Omicron virus has gained dominance worldwide, its continual
evolution with unpredictable mutations and patterns has revoked all authorized …

SARS-CoV-2 has the capacity to evolve mutations that escape vaccine-and infection-
acquired immunity and antiviral drugs. A variant-agnostic therapeutic agent that protects …

HH‐120, a recently developed IgM‐like ACE2 fusion protein with broad‐spectrum
neutralizing activity against all ACE2‐utilizing coronaviruses, has been developed as a …

Host cell infection by SARS-CoV-2, similar to that by HIV-1, is driven by a conformationally
metastable and highly glycosylated surface entry protein complex, and infection by these …

With increasing resistance of SARS-CoV-2 variants to antibodies, there is interest in
developing entry inhibitors that target essential receptor-binding regions of the viral Spike …

As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants have been
causing increasingly serious drug resistance problem, development of broadly effective and …

The Spike of SARS-CoV-2 recognizes a transmembrane protease, angiotensin-converting
enzyme 2 (ACE2), on host cells to initiate infection. Soluble derivatives of ACE2, in which …

Objective This study aimed to investigate the international scientific output regarding the
relationship between COVID-19 and cardiovascular diseases (CVDs) through a bibliometric …