Toxicological and pathophysiological roles of reactive oxygen and nitrogen species
'Oxidative and Nitrative Stress in Toxicology and Disease'was the subject of a symposium
held at the EUROTOX meeting in Dresden 15th September 2009. Reactive oxygen (ROS) …
held at the EUROTOX meeting in Dresden 15th September 2009. Reactive oxygen (ROS) …
3-Hydroxykynurenine: an intriguing molecule exerting dual actions in the central nervous system
AL Colín-González, PD Maldonado, A Santamaría - Neurotoxicology, 2013 - Elsevier
Kynurenine pathway is gaining attention due to the many metabolic processes in which it
has been involved. The tryptophan conversion into several other metabolites through this …
has been involved. The tryptophan conversion into several other metabolites through this …
Hydrogen peroxide is the major oxidant product of xanthine oxidase
EE Kelley, NKH Khoo, NJ Hundley, UZ Malik… - Free Radical Biology …, 2010 - Elsevier
Xanthine oxidase (XO) is a critical source of reactive oxygen species (ROS) in inflammatory
disease. Focus, however, has centered almost exclusively on XO-derived superoxide …
disease. Focus, however, has centered almost exclusively on XO-derived superoxide …
Lactobacillus paracasei CCFM1229 and Lactobacillus rhamnosus CCFM1228 Alleviated Depression- and Anxiety-Related Symptoms of Chronic Stress-Induced …
Depression is a common mood disorder that affects around 350 million people worldwide.
We studied the effect of supplementation with Lactobacillus strains for the treatment of …
We studied the effect of supplementation with Lactobacillus strains for the treatment of …
Responses of differentiated MC3T3-E1 osteoblast-like cells to reactive oxygen species
MC3T3-E1 osteoblast-like cells represent a suitable model for studying osteogenic
development in vitro. The current investigation extends our previous work on the response of …
development in vitro. The current investigation extends our previous work on the response of …
Ser9 phosphorylation of mitochondrial GSK-3β is a primary mechanism of cardiomyocyte protection by erythropoietin against oxidant-induced apoptosis
K Ohori, T Miura, M Tanno, T Miki… - American Journal …, 2008 - journals.physiology.org
The aim of this study was to determine the role of GSK-3β in cardiomyocyte protection
afforded by erythropoietin (EPO) against oxidant stress-induced apoptosis. Treatment with …
afforded by erythropoietin (EPO) against oxidant stress-induced apoptosis. Treatment with …
Oxidative stress enhances neurodegeneration markers induced by herpes simplex virus type 1 infection in human neuroblastoma cells
S Santana, I Sastre, M Recuero, MJ Bullido, J Aldudo - PLoS One, 2013 - journals.plos.org
Mounting evidence suggests that Herpes simplex virus type 1 (HSV-1) is involved in the
pathogenesis of Alzheimer's disease (AD). Previous work from our laboratory has shown …
pathogenesis of Alzheimer's disease (AD). Previous work from our laboratory has shown …
Lower bone mineral density in children with type 1 diabetes is associated with poor glycemic control and higher serum ICAM-1 and urinary isoprostane levels
K Heilman, M Zilmer, K Zilmer, V Tillmann - Journal of bone and mineral …, 2009 - Springer
The purpose of the study was to investigate bone mineral density (BMD) in children with type
1 diabetes (DM1) and to establish the relationships between BMD, physical activity …
1 diabetes (DM1) and to establish the relationships between BMD, physical activity …
[HTML][HTML] Protective mechanism of grape seed oil on carbon tetrachloride-induced brain damage in γ-irradiated rats
AFM Ismail, FSM Moawed, MA Mohamed - Journal of Photochemistry and …, 2015 - Elsevier
This study investigated the possible beneficial effects of grape seed oil (GSO) on carbon
tetrachloride (CCl 4)-induced acute neurotoxicity in γ-irradiated rats. A statistical significant …
tetrachloride (CCl 4)-induced acute neurotoxicity in γ-irradiated rats. A statistical significant …
Downregulation of cell survival signalling pathways and increased cell damage in hydrogen peroxide‐treated human renal proximal tubular cells by alpha …
M Andreucci, G Fuiano, P Presta, G Lucisano… - Cell …, 2009 - Wiley Online Library
Objective: Erythropoietin has been shown to have a protective effect in certain models of
ischaemia‐reperfusion, and in some cases the protection has been correlated with …
ischaemia‐reperfusion, and in some cases the protection has been correlated with …