Why primate models matter
Research involving nonhuman primates (NHPs) has played a vital role in many of the
medical and scientific advances of the past century. NHPs are used because of their …
medical and scientific advances of the past century. NHPs are used because of their …
Epigenetics and the biological definition of gene× environment interactions
MJ Meaney - Child development, 2010 - Wiley Online Library
Variations in phenotype reflect the influence of environmental conditions during
development on cellular functions, including that of the genome. The recent integration of …
development on cellular functions, including that of the genome. The recent integration of …
From mice to men: what can we learn about personality from animal research?
SD Gosling - Psychological bulletin, 2001 - psycnet.apa.org
The author explores the viability of a comparative approach to personality research. A
review of the diverse animal-personality literature suggests that (a) most research uses trait …
review of the diverse animal-personality literature suggests that (a) most research uses trait …
Looking on the bright side of serotonin transporter gene variation
JR Homberg, KP Lesch - Biological psychiatry, 2011 - Elsevier
Converging evidence indicates an association of the short (s), low-expressing variant of the
repeat length polymorphism, serotonin transporter-linked polymorphic region (5-HTTLPR) …
repeat length polymorphism, serotonin transporter-linked polymorphic region (5-HTTLPR) …
Maternal care and the development of stress responses
Stress is a risk factor for a variety of illnesses, ranging from auto-immune disorders to mental
illness. The pathways through which stressful events can promote the development of such …
illness. The pathways through which stressful events can promote the development of such …
The developmental origins of anxiety
Anxiety is a mental state that is elicited in anticipation of threat or potential threat. Sensations
of anxiety are a normal part of human experience, but excessive or inappropriate anxiety …
of anxiety are a normal part of human experience, but excessive or inappropriate anxiety …
[HTML][HTML] Serotonin transporter: gene, genetic disorders, and pharmacogenetics
DL Murphy, A Lerner, G Rudnick… - Molecular …, 2004 - triggered.stanford.clockss.org
The highly evolutionarily conserved serotonin transporter (SERT) regulates the entire
serotoninergic system and its receptors via mod-ulation of extracellular fluid serotonin …
serotoninergic system and its receptors via mod-ulation of extracellular fluid serotonin …
Early experience and serotonin transporter gene variation interact to influence primate CNS function
Nonhuman primates offer unique opportunities to study the effects of genes, environments,
and their interaction, on physiology and complex behavior. We examined genotype and …
and their interaction, on physiology and complex behavior. We examined genotype and …
Impulsivity, aggression, and serotonin: a molecular psychobiological perspective
KP Lesch, U Merschdorf - Behavioral sciences & the law, 2000 - Wiley Online Library
The expression of aggressiveness, which constitutes many facets of behavior, is influenced
by a complex interaction of biologic, psychologic, and social variables. Even though …
by a complex interaction of biologic, psychologic, and social variables. Even though …