The glymphatic system: a beginner's guide
NA Jessen, ASF Munk, I Lundgaard… - Neurochemical …, 2015 - Springer
The glymphatic system is a recently discovered macroscopic waste clearance system that
utilizes a unique system of perivascular tunnels, formed by astroglial cells, to promote …
utilizes a unique system of perivascular tunnels, formed by astroglial cells, to promote …
Brain microvascular pericytes in vascular cognitive impairment and dementia
Pericytes are unique, multi-functional mural cells localized at the abluminal side of the
perivascular space in microvessels. Originally discovered in 19th century, pericytes had …
perivascular space in microvessels. Originally discovered in 19th century, pericytes had …
A spatially resolved atlas of the human lung characterizes a gland-associated immune niche
E Madissoon, AJ Oliver, V Kleshchevnikov… - Nature Genetics, 2023 - nature.com
Single-cell transcriptomics has allowed unprecedented resolution of cell types/states in the
human lung, but their spatial context is less well defined. To (re) define tissue architecture of …
human lung, but their spatial context is less well defined. To (re) define tissue architecture of …
Leptin-receptor-expressing mesenchymal stromal cells represent the main source of bone formed by adult bone marrow
BO Zhou, R Yue, MM Murphy, JG Peyer, SJ Morrison - Cell stem cell, 2014 - cell.com
Studies of the identity and physiological function of mesenchymal stromal cells (MSCs) have
been hampered by a lack of markers that permit both prospective identification and fate …
been hampered by a lack of markers that permit both prospective identification and fate …
[HTML][HTML] Pericyte-expressed Tie2 controls angiogenesis and vessel maturation
M Teichert, L Milde, A Holm, L Stanicek… - Nature …, 2017 - nature.com
The Tie receptors with their Angiopoietin ligands act as regulators of angiogenesis and
vessel maturation. Tie2 exerts its functions through its supposed endothelial-specific …
vessel maturation. Tie2 exerts its functions through its supposed endothelial-specific …
Secretion of shh by a neurovascular bundle niche supports mesenchymal stem cell homeostasis in the adult mouse incisor
Mesenchymal stem cells (MSCs) are typically defined by their in vitro characteristics, and as
a consequence the in vivo identity of MSCs and their niches are poorly understood. To …
a consequence the in vivo identity of MSCs and their niches are poorly understood. To …
Capillary and arteriolar pericytes attract innate leukocytes exiting through venules and'instruct'them with pattern-recognition and motility programs
Coordinated navigation within tissues is essential for cells of the innate immune system to
reach the sites of inflammatory processes, but the signals involved are incompletely …
reach the sites of inflammatory processes, but the signals involved are incompletely …
In search of the in vivo identity of mesenchymal stem cells
L da Silva Meirelles, AI Caplan, NB Nardi - Stem cells, 2008 - academic.oup.com
In spite of the advances in the knowledge of adult stem cells (ASCs) during the past few
years, their natural activities in vivo are still poorly understood. Mesenchymal stem cells …
years, their natural activities in vivo are still poorly understood. Mesenchymal stem cells …
An ocular glymphatic clearance system removes β-amyloid from the rodent eye
Despite high metabolic activity, the retina and optic nerve head lack traditional lymphatic
drainage. We here identified an ocular glymphatic clearance route for fluid and wastes via …
drainage. We here identified an ocular glymphatic clearance route for fluid and wastes via …
Perivascular cells for regenerative medicine
Mesenchymal stem/stromal cells (MSC) are currently the best candidate therapeutic cells for
regenerative medicine related to osteoarticular, muscular, vascular and inflammatory …
regenerative medicine related to osteoarticular, muscular, vascular and inflammatory …