Physics-inspired structural representations for molecules and materials

F Musil, A Grisafi, AP Bartók, C Ortner… - Chemical …, 2021 - ACS Publications
The first step in the construction of a regression model or a data-driven analysis, aiming to
predict or elucidate the relationship between the atomic-scale structure of matter and its …

The SIRAH force field: a suite for simulations of complex biological systems at the coarse-grained and multiscale levels

F Klein, M Soñora, LH Santos, EN Frigini… - Journal of structural …, 2023 - Elsevier
The different combinations of molecular dynamics simulations with coarse-grained
representations have acquired considerable popularity among the scientific community …

LiPyphilic: A Python toolkit for the analysis of lipid membrane simulations

P Smith, CD Lorenz - Journal of chemical theory and computation, 2021 - ACS Publications
Molecular dynamics simulations are now widely used to study emergent phenomena in lipid
membranes with complex compositions. Here, we present LiPyphilic—a fast, fully tested …

Layer-by-layer unsupervised clustering of statistically relevant fluctuations in noisy time-series data of complex dynamical systems

M Becchi, F Fantolino, GM Pavan - … of the National Academy of Sciences, 2024 - pnas.org
Complex systems are typically characterized by intricate internal dynamics that are often
hard to elucidate. Ideally, this requires methods that allow to detect and classify in an …

Living supramolecular polymerization of fluorinated cyclohexanes

O Shyshov, SV Haridas, L Pesce, H Qi, A Gardin… - Nature …, 2021 - nature.com
The development of powerful methods for living covalent polymerization has been a key
driver of progress in organic materials science. While there have been remarkable reports …

Mechanistic understanding from molecular dynamics in pharmaceutical research 2: lipid membrane in drug design

T Róg, M Girych, A Bunker - Pharmaceuticals, 2021 - mdpi.com
We review the use of molecular dynamics (MD) simulation as a drug design tool in the
context of the role that the lipid membrane can play in drug action, ie, the interaction …

Classifying soft self-assembled materials via unsupervised machine learning of defects

A Gardin, C Perego, G Doni, GM Pavan - Communications Chemistry, 2022 - nature.com
Unlike molecular crystals, soft self-assembled fibers, micelles, vesicles, etc., exhibit a certain
order in the arrangement of their constitutive monomers but also high structural dynamicity …

Integrating machine learning in the coarse-grained molecular simulation of polymers

E Ricci, N Vergadou - The Journal of Physical Chemistry B, 2023 - ACS Publications
Machine learning (ML) is having an increasing impact on the physical sciences,
engineering, and technology and its integration into molecular simulation frameworks holds …

DADApy: Distance-based analysis of data-manifolds in Python

A Glielmo, I Macocco, D Doimo, M Carli, C Zeni, R Wild… - Patterns, 2022 - cell.com
DADApy is a Python software package for analyzing and characterizing high-dimensional
data manifolds. It provides methods for estimating the intrinsic dimension and the probability …

Detecting dynamic domains and local fluctuations in complex molecular systems via timelapse neighbors shuffling

M Crippa, A Cardellini, C Caruso… - Proceedings of the …, 2023 - National Acad Sciences
It is known that the behavior of many complex systems is controlled by local dynamic
rearrangements or fluctuations occurring within them. Complex molecular systems …