Metabolic engineering in the host Yarrowia lipolytica

AM Abdel-Mawgoud, KA Markham, CM Palmer… - Metabolic …, 2018 - Elsevier
The nonconventional, oleaginous yeast, Yarrowia lipolytica is rapidly emerging as a
valuable host for the production of a variety of both lipid and nonlipid chemical products …

Acetate as a potential feedstock for the production of value-added chemicals: metabolism and applications

Y Kim, S Lama, D Agrawal, V Kumar, S Park - Biotechnology Advances, 2021 - Elsevier
Acetate is regarded as a promising carbon feedstock in biological production owing to its
possible derivation from C 1 gases such as CO, CO 2 and methane. To best use of acetate …

Bioconversion of volatile fatty acids into lipids by the oleaginous yeast Yarrowia lipolytica

P Fontanille, V Kumar, G Christophe, R Nouaille… - Bioresource …, 2012 - Elsevier
The valorization of volatile fatty acids into microbial lipids by the oleaginous yeast Yarrowia
lipolytica was investigated. Therefore, a two-stage fed-batch strategy was designed: the …

The fungal pathogen Candida albicans autoinduces hyphal morphogenesis by raising extracellular pH

S Vylkova, AJ Carman, HA Danhof, JR Collette, H Zhou… - MBio, 2011 - Am Soc Microbiol
ABSTRACT pH homeostasis is critical for all organisms; in the fungal pathogen Candida
albicans, pH adaptation is critical for virulence in distinct host niches. We demonstrate that …

Methanosaeta, the forgotten methanogen?

KS Smith, C Ingram-Smith - Trends in microbiology, 2007 - cell.com
Although the aceticlastic methanoarchaea Methanosarcina and Methanosaeta employ
different enzymes to catalyze the first step of aceticlastic methanogenesis, it has long been …

Adaptive Response and Tolerance to Acetic Acid in Saccharomyces cerevisiae and Zygosaccharomyces bailii: A Physiological Genomics Perspective

M Palma, JF Guerreiro, I Sá-Correia - Frontiers in Microbiology, 2018 - frontiersin.org
Acetic acid is an important microbial growth inhibitor in the food industry; it is used as a
preservative in foods and beverages and is produced during normal yeast metabolism in …

Complete and efficient conversion of plant cell wall hemicellulose into high-value bioproducts by engineered yeast

L Sun, JW Lee, S Yook, S Lane, Z Sun, SR Kim… - Nature …, 2021 - nature.com
Plant cell wall hydrolysates contain not only sugars but also substantial amounts of acetate,
a fermentation inhibitor that hinders bioconversion of lignocellulose. Despite the toxic and …

Molecular mechanisms of Saccharomyces cerevisiae stress adaptation and programmed cell death in response to acetic acid

S Giannattasio, N Guaragnella, M Ždralević… - Frontiers in …, 2013 - frontiersin.org
Beyond its classical biotechnological applications such as food and beverage production or
as a cell factory, the yeast Saccharomyces cerevisiae is a valuable model organism to study …

The Path to Triacylglyceride Obesity in the sta6 Strain of Chlamydomonas reinhardtii

U Goodenough, I Blaby, D Casero, SD Gallaher… - Eukaryotic …, 2014 - Am Soc Microbiol
When the sta6 (starch-null) strain of the green microalga Chlamydomonas reinhardtii is
nitrogen starved in acetate and then “boosted” after 2 days with additional acetate, the cells …

[HTML][HTML] Mechanisms underlying lactic acid tolerance and its influence on lactic acid production in Saccharomyces cerevisiae

A Peetermans, MR Foulquié-Moreno… - Microbial Cell, 2021 - ncbi.nlm.nih.gov
One of the major bottlenecks in lactic acid production using microbial fermentation is the
detrimental influence lactic acid accumulation poses on the lactic acid producing cells. The …