FTO–a common genetic basis for obesity and cancer

N Lan, Y Lu, Y Zhang, S Pu, H Xi, X Nie, J Liu… - Frontiers in …, 2020 - frontiersin.org
In recent years, the prevalence of obesity and cancer have been rising. Since this poses a
serious threat to human health, the relationship between the two has attracted much …

RBL2/p130 is a direct AKT target and is required to induce apoptosis upon AKT inhibition in lung cancer and mesothelioma cell lines

F Pentimalli, IM Forte, L Esposito, P Indovina… - Oncogene, 2018 - nature.com
The retinoblastoma (RB) protein family includes RB1/p105, RBL1/p107, and RBL2/p130,
which are key factors in cell-cycle regulation and stand at the crossroads of multiple …