Diabetic sensorimotor peripheral neuropathy (DSPN) is a serious complication of diabetes
mellitus and is associated with increased mortality, lower-limb amputations and distressing …

Pain medication plays an important role in the treatment of acute and chronic pain
conditions, but some drugs, opioids in particular, have been overprescribed or prescribed …

Purpose Diabetic peripheral neuropathy (DPN) is the commonest cause of neuropathy
worldwide, and its prevalence increases with the duration of diabetes. It affects …

Neuropathic pain is a frequent condition caused by a lesion or disease of the central or
peripheral somatosensory nervous system. A frequent cause of peripheral neuropathic pain …

Neuropathic pain is caused by disease or injury of the nervous system and includes various
chronic conditions that, together, affect up to 8% of the population. A substantial body of …

Neuropathic pain has been a very active and productive clinical research field over the last
15 years. Studies have concerned multiple aspects of these complex chronic pain …

There is tremendous interpatient variability in the response to analgesic therapy (even for
efficacious treatments), which can be the source of great frustration in clinical practice. This …

Diabetic peripheral neuropathy (DPN) is a common chronic complication of diabetes
mellitus. It leads to distressing and expensive clinical sequelae such as foot ulceration, leg …

Disabling neuropathic pain (NeuP) is a common sequel of diabetic peripheral neuropathy
(DPN). We aimed to characterise the sensory phenotype of patients with and without NeuP …

Background New drug treatments, clinical trials, and standards of quality for assessment of
evidence justify an update of evidence-based recommendations for the pharmacological …