Concentration gradient generation methods based on microfluidic systems

X Wang, Z Liu, Y Pang - RSC advances, 2017 - pubs.rsc.org
Various concentration gradient generation methods based on microfluidic systems are
summarized in this paper. The review covers typical structural characteristics, gradient …

Concentration gradients in material sciences: methods to design and biomedical applications

D Hua, R Xiong, K Braeckmans… - Advanced Functional …, 2021 - Wiley Online Library
Concentration gradients are at the basis of many natural phenomena and hold great
importance in human and plant biology. This basic phenomenon has inspired many material …

An antibiotic concentration gradient microfluidic device integrating surface-enhanced Raman spectroscopy for multiplex antimicrobial susceptibility testing

SJ Lin, PH Chao, HW Cheng, JK Wang, YL Wang… - Lab on a Chip, 2022 - pubs.rsc.org
Antimicrobial susceptibility testing (AST) is a key measure in clinical microbiology
laboratories to enable appropriate antimicrobial administration. During an AST, the …

A review of chemical gradient systems for cell analysis

H Somaweera, A Ibraguimov, D Pappas - Analytica chimica acta, 2016 - Elsevier
Microfluidic spatial and temporal gradient generators have played an important role in many
biological assays such as in the analysis of wound healing, inflammation, and cancer …

High-throughput screening approaches and combinatorial development of biomaterials using microfluidics

D Barata, C van Blitterswijk, P Habibovic - Acta biomaterialia, 2016 - Elsevier
From the first microfluidic devices used for analysis of single metabolic by-products to highly
complex multicompartmental co-culture organ-on-chip platforms, efforts of many …

Microfluidic devices having isolation pens and methods of testing biological micro-objects with same

MP White, ED Hobbs, JT Nevill, D Malleo… - US Patent …, 2018 - Google Patents
A microfluidic device can comprise at least one swept region that is fluidically connected to
unswept regions. The fluidic connections between the swept region and the unswept …

Pens for biological micro-objects

KT Chapman, IY Khandros, GL Mathieu… - US Patent …, 2018 - Google Patents
Individual biological micro-objects can be deterministically selected and moved into holding
pens in a micro-fluidic device. A flow of a first liquid medium can be provided to the pens …

Microfluidics and cancer analysis: cell separation, cell/tissue culture, cell mechanics, and integrated analysis systems

D Pappas - Analyst, 2016 - pubs.rsc.org
Among the growing number of tools available for cancer studies, microfluidic systems have
emerged as a promising analytical tool to elucidate cancer cell and tumor function …

The latest advances in high content screening in microfluidic devices

W Liu, J Wang, H Qi, Q Jiao, L Wu… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction High content screening (HCS) is an important tool for drug screening. However,
the potential of HCS in the field of drug screening and synthetic biology is limited by …

Methods, systems and kits for in-pen assays

TA Lionberger, ME Fowler, JM Phillip… - US Patent …, 2021 - Google Patents
2019-11-13 Assigned to Berkeley Lights, Inc. reassignment Berkeley Lights, Inc.
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …