Assembly and maintenance of lipids at the bacterial outer membrane
E Lundstedt, D Kahne, N Ruiz - Chemical reviews, 2020 - ACS Publications
The outer membrane of Gram-negative bacteria is essential for their survival in harsh
environments and provides intrinsic resistance to many antibiotics. This membrane is …
environments and provides intrinsic resistance to many antibiotics. This membrane is …
The phosphopantetheinyl transferases: catalysis of a post-translational modification crucial for life
Covering: up to 2013 Although holo-acyl carrier protein synthase, AcpS, a
phosphopantetheinyl transferase (PPTase), was characterized in the 1960s, it was not until …
phosphopantetheinyl transferase (PPTase), was characterized in the 1960s, it was not until …
The Essential Genome of Escherichia coli K-12
Transposon-directed insertion site sequencing (TraDIS) is a high-throughput method
coupling transposon mutagenesis with short-fragment DNA sequencing. It is commonly used …
coupling transposon mutagenesis with short-fragment DNA sequencing. It is commonly used …
Structure of the essential inner membrane lipopolysaccharide–PbgA complex
Lipopolysaccharide (LPS) resides in the outer membrane of Gram-negative bacteria where it
is responsible for barrier function,. LPS can cause death as a result of septic shock, and its …
is responsible for barrier function,. LPS can cause death as a result of septic shock, and its …
Regulatory mechanisms of lipopolysaccharide synthesis in Escherichia coli
S Shu, W Mi - Nature Communications, 2022 - nature.com
Lipopolysaccharide (LPS) is an essential glycolipid and forms a protective permeability
barrier for most Gram-negative bacteria. In E. coli, LPS levels are under feedback control …
barrier for most Gram-negative bacteria. In E. coli, LPS levels are under feedback control …
Border control: regulating LPS biogenesis
RL Guest, ST Rutherford, TJ Silhavy - Trends in Microbiology, 2021 - cell.com
The outer membrane (OM) is a defining feature of Gram-negative bacteria that serves as a
permeability barrier and provides rigidity to the cell. Critical to OM function is establishing …
permeability barrier and provides rigidity to the cell. Critical to OM function is establishing …
YejM modulates activity of the YciM/FtsH protease complex to prevent lethal accumulation of lipopolysaccharide
RL Guest, D Samé Guerra, M Wissler, J Grimm… - MBio, 2020 - Am Soc Microbiol
Lipopolysaccharide (LPS) is an essential glycolipid present in the outer membrane (OM) of
many Gram-negative bacteria. Balanced biosynthesis of LPS is critical for cell viability; too …
many Gram-negative bacteria. Balanced biosynthesis of LPS is critical for cell viability; too …
Lipid trafficking across the Gram-negative cell envelope
R Shrivastava, SS Chng - Journal of Biological Chemistry, 2019 - ASBMB
The outer membrane (OM) of Gram-negative bacteria exhibits unique lipid asymmetry, with
lipopolysaccharides (LPS) residing in the outer leaflet and phospholipids (PLs) in the inner …
lipopolysaccharides (LPS) residing in the outer leaflet and phospholipids (PLs) in the inner …
An essential membrane protein modulates the proteolysis of LpxC to control lipopolysaccharide synthesis in Escherichia coli
EM Fivenson, TG Bernhardt - MBio, 2020 - Am Soc Microbiol
Gram-negative bacteria are surrounded by a complex cell envelope that includes two
membranes. The outer membrane prevents many drugs from entering these cells and is thus …
membranes. The outer membrane prevents many drugs from entering these cells and is thus …
Delivery of cardiolipins to the Salmonella outer membrane is necessary for survival within host tissues and virulence
The outer membrane (OM) of Gram-negative bacteria is an asymmetric lipid bilayer that
serves as a barrier to the environment. During infection, Gram-negative bacteria remodel …
serves as a barrier to the environment. During infection, Gram-negative bacteria remodel …