Oxidative stress, inflammation and hormesis: The role of dietary and lifestyle modifications on aging

V Sharma, MM Mehdi - Neurochemistry international, 2023 - Elsevier
Oxidative stress (OS) is primarily caused by the formation of free radicals and reactive
oxygen species; it is considered as one of the prominent factors in slowing down and …

Oxygen consumption and usage during physical exercise: the balance between oxidative stress and ROS-dependent adaptive signaling

Z Radak, Z Zhao, E Koltai, H Ohno… - Antioxidants & redox …, 2013 - liebertpub.com
The complexity of human DNA has been affected by aerobic metabolism, including
endurance exercise and oxygen toxicity. Aerobic endurance exercise could play an …

Exercise prevents weight gain and alters the gut microbiota in a mouse model of high fat diet-induced obesity

CC Evans, KJ LePard, JW Kwak, MC Stancukas… - PloS one, 2014 - journals.plos.org
Background Diet-induced obesity (DIO) is a significant health concern which has been
linked to structural and functional changes in the gut microbiota. Exercise (Ex) is effective in …

Chemistry and biochemistry of lipid peroxidation products

F Guéraud, M Atalay, N Bresgen, A Cipak… - Free radical …, 2010 - Taylor & Francis
Oxidative stress and resulting lipid peroxidation is involved in various and numerous
pathological states including inflammation, atherosclerosis, neurodegenerative diseases …

Positive aspects of oxidative stress at different levels of the human body: A review

G Jîtcă, BE Ősz, A Tero-Vescan, AP Miklos, CM Rusz… - Antioxidants, 2022 - mdpi.com
Oxidative stress is the subject of numerous studies, most of them focusing on the negative
effects exerted at both molecular and cellular levels, ignoring the possible benefits of free …

Hormesis in aging

SIS Rattan - Ageing research reviews, 2008 - Elsevier
Hormesis in aging is represented by mild stress-induced stimulation of protective
mechanisms in cells and organisms resulting in biologically beneficial effects. Single or …

Exercise, inflammation, and innate immunity

JA Woods, VJ Vieira, KT Keylock - Immunology and allergy clinics of North …, 2009 - Elsevier
Exercise has beneficial effects on chronic disease, and the drive to understand the
mechanisms of these benefits is strong. This article presents several compelling potential …

The exercise-induced stress response of skeletal muscle, with specific emphasis on humans

JP Morton, AC Kayani, A McArdle, B Drust - Sports medicine, 2009 - Springer
Skeletal muscle adapts to the stress of contractile activity via changes in gene expression to
yield an increased content of a family of highly conserved cytoprotective proteins known as …

The chaperone balance hypothesis: The importance of the extracellular to intracellular HSP70 ratio to inflammation‐driven type 2 diabetes, the effect of exercise, and …

M Krause, TG Heck, A Bittencourt… - Mediators of …, 2015 - Wiley Online Library
Recent evidence shows divergence between the concentrations of extracellular 70 kDa heat
shock protein [eHSP70] and its intracellular concentrations [iHSP70] in people with type 2 …

Exercise, heat shock proteins and insulin resistance

AE Archer, AT Von Schulze… - … Transactions of the …, 2018 - royalsocietypublishing.org
Best known as chaperones, heat shock proteins (HSPs) also have roles in cell signalling
and regulation of metabolism. Rodent studies demonstrate that heat treatment, transgenic …