Endophytic fungi—alternative sources of cytotoxic compounds: a review

F Uzma, CD Mohan, A Hashem, NM Konappa… - Frontiers in …, 2018 - frontiersin.org
Cancer is a major cause of death worldwide, with an increasing number of cases being
reported annually. The elevated rate of mortality necessitates a global challenge to explore …

Endophytic fungi: a source of potential antifungal compounds

SK Deshmukh, MK Gupta, V Prakash, S Saxena - Journal of Fungi, 2018 - mdpi.com
The emerging and reemerging forms of fungal infections encountered in the course of
allogeneic bone marrow transplantations, cancer therapy, and organ transplants have …

Bioactive Secondary Metabolites of the Genus Diaporthe and Anamorph Phomopsis from Terrestrial and Marine Habitats and Endophytes: 2010–2019

TC Xu, YH Lu, JF Wang, ZQ Song, YG Hou, SS Liu… - Microorganisms, 2021 - mdpi.com
The genus Diaporthe and its anamorph Phomopsis are distributed worldwide in many
ecosystems. They are regarded as potential sources for producing diverse bioactive …

Contribution of endophytes towards improving plant bioactive metabolites: a rescue option against red-taping of medicinal plants

S Tsipinana, S Husseiny, KA Alayande… - Frontiers in Plant …, 2023 - frontiersin.org
Medicinal plants remain a valuable source for natural drug bioprospecting owing to their
multi-target spectrum. However, their use as raw materials for novel drug synthesis has been …

Extracts of endophytic fungi from leaves of selected Nigerian ethnomedicinal plants exhibited antioxidant activity

M Ibrahim, E Oyebanji, M Fowora, A Aiyeolemi… - … Medicine and Therapies, 2021 - Springer
Background Plants with an ethnobotanical history are known to harbor diverse group of
endophytic fungi, which constitute major natural sources of bioactive compounds. In the …

Mass spectrometry-based technology and workflows for studying the chemistry of fungal endophyte derived bioactive compounds

P Gupta, A Verma, N Rai, AK Singh… - ACS Chemical …, 2021 - ACS Publications
Bioactive compounds have gained substantial attention in research and have conferred
great advancements in the industrial and pharmacological fields. Highly diverse fungi and …

Anti-Alzheimer's natural products derived from plant endophytic fungi

J Zhu, Z Wang, L Song, W Fu, L Liu - Molecules, 2023 - mdpi.com
Alzheimer's is the most common cause of dementia worldwide and seriously affects patients'
daily tasks. Plant endophytic fungi are known for providing novel and unique secondary …

Anti-inflammatory and antioxidant effects of Chaetoglobosin Vb in LPS-induced RAW264. 7 cells: Achieved via the MAPK and NF-κB signaling pathways

H Zhang, Q Guo, Z Liang, M Wang, B Wang… - Food and Chemical …, 2021 - Elsevier
There are few reports on the biological activities of chaetoglobosin V b (Cha V b)(a
cytochalasin alkaloid). In this study, we investigated the molecular mechanisms underlying …

Microbial acetylcholinesterase inhibitors for Alzheimer's therapy: recent trends on extraction, detection, irradiation-assisted production improvement and nano …

AG Zaki, ESR El-Sayed, M Abd Elkodous… - Applied Microbiology …, 2020 - Springer
Neurodegenerative disorders especially Alzheimer's disease (AD) are significantly
threatening the public health. Acetylcholinesterase (AChE) inhibitors are compounds of …

Brazilian plants: An unexplored source of endophytes as producers of active metabolites

DC Savi, R Aluizio, C Glienke - Planta Medica, 2019 - thieme-connect.com
Brazil has an extraordinary biodiversity, and for many years, has been classified as the first
of 17 countries with a mega diversity, with 22% of the total plants in the world (more than 55 …