A review of multivariate methods for multimodal fusion of brain imaging data

J Sui, T Adali, Q Yu, J Chen, VD Calhoun - Journal of neuroscience …, 2012 - Elsevier
The development of various neuroimaging techniques is rapidly improving the
measurements of brain function/structure. However, despite improvements in individual …

A review of multivariate analyses in imaging genetics

J Liu, VD Calhoun - Frontiers in neuroinformatics, 2014 - frontiersin.org
Recent advances in neuroimaging technology and molecular genetics provide the unique
opportunity to investigate genetic influence on the variation of brain attributes. Since the year …

A three-way parallel ICA approach to analyze links among genetics, brain structure and brain function

VM Vergara, A Ulloa, VD Calhoun, D Boutte, J Chen… - Neuroimage, 2014 - Elsevier
Multi-modal data analysis techniques, such as the Parallel Independent Component
Analysis (pICA), are essential in neuroscience, medical imaging and genetic studies. The …

Genetic associations of brain structural networks in schizophrenia: a preliminary study

K Jagannathan, VD Calhoun, J Gelernter… - Biological …, 2010 - Elsevier
BACKGROUND: Schizophrenia is a complex genetic disorder, with multiple putative risk
genes and many reports of reduced cortical gray matter. Identifying the genetic loci …

A pilot multivariate parallel ICA study to investigate differential linkage between neural networks and genetic profiles in schizophrenia

SA Meda, K Jagannathan, J Gelernter, VD Calhoun… - Neuroimage, 2010 - Elsevier
Understanding genetic influences on both healthy and disordered brain function is a major
focus in psychiatric neuroimaging. We utilized task-related imaging findings from an fMRI …

Multifaceted genomic risk for brain function in schizophrenia

J Chen, VD Calhoun, GD Pearlson, S Ehrlich… - Neuroimage, 2012 - Elsevier
Recently, deriving candidate endophenotypes from brain imaging data has become a
valuable approach to study genetic influences on schizophrenia (SZ), whose …

Multivariate imaging genetics study of MRI gray matter volume and SNPs reveals biological pathways correlated with brain structural differences in attention deficit …

S Khadka, GD Pearlson, VD Calhoun, J Liu… - Frontiers in …, 2016 - frontiersin.org
Background Attention deficit hyperactivity disorder (ADHD) is a prevalent
neurodevelopmental disorder affecting children, adolescents, and adults. Its etiology is not …

Convergent approaches for defining functional imaging endophenotypes in schizophrenia

G Pearlson, VD Calhoun - Frontiers in human neuroscience, 2009 - frontiersin.org
In complex genetic disorders such as schizophrenia, endophenotypes have potential utility
both in identifying risk genes and in illuminating pathophysiology. This is due to their …

Genetic markers of white matter integrity in schizophrenia revealed by parallel ICA

CN Gupta, J Chen, J Liu, E Damaraju… - Frontiers in human …, 2015 - frontiersin.org
It is becoming a consensus that white matter integrity is compromised in schizophrenia (SZ),
however the underlying genetics remains elusive. Evidence suggests a polygenic basis of …

Translational potential of neuroimaging genomic analyses to diagnosis and treatment in mental disorders

J Chen, J Liu, VD Calhoun - Proceedings of the IEEE, 2019 - ieeexplore.ieee.org
Imaging genomics focuses on characterizing genomic influence on the variation of
neurobiological traits, holding promise for illuminating the pathogenesis, reforming the …