The pangenome refers to a collection of genomic sequence found in the entire species or
population rather than in a single individual; the sequence can be core, present in all …

Highlights•Pan-genomes represent the complex genomic diversity found in plant
species.•Novel approaches are under development to enable more complex pan-genome …

Population-level comparisons of prokaryotic genomes must take into account the substantial
differences in gene content resulting from horizontal gene transfer, gene duplication and …

The oral microbiome plays key roles in human biology, health, and disease, but little is
known about the global diversity, variation, or evolution of this microbial community. To …

The existence of large amounts of within-species genome content variability is puzzling.
Population genetics tells us that fitness effects of new variants—either deleterious, neutral or …

Motivation Pangenome graphs provide a complete representation of the mutual alignment of
collections of genomes. These models offer the opportunity to study the entire genomic …

The EDGAR platform, a web server providing databases of precomputed orthology data for
thousands of microbial genomes, is one of the most established tools in the field of …

Peatlands are crucial sinks for atmospheric carbon but are critically threatened due to
warming climates. Sphagnum (peat moss) species are keystone members of peatland …

Many bacterial species are represented by a pan-genome, whose genetic repertoire far
outstrips that of any single bacterial genome. Here we investigate how a bacterial pan …

Background Cataloguing the distribution of genes within natural bacterial populations is
essential for understanding evolutionary processes and the genetic basis of adaptation …