Liver metastases
Liver metastases are commonly detected in a range of malignancies including colorectal
cancer (CRC), pancreatic cancer, melanoma, lung cancer and breast cancer, although CRC …
cancer (CRC), pancreatic cancer, melanoma, lung cancer and breast cancer, although CRC …
Emerging insights of tumor heterogeneity and drug resistance mechanisms in lung cancer targeted therapy
ZF Lim, PC Ma - Journal of hematology & oncology, 2019 - Springer
The biggest hurdle to targeted cancer therapy is the inevitable emergence of drug
resistance. Tumor cells employ different mechanisms to resist the targeting agent. Most …
resistance. Tumor cells employ different mechanisms to resist the targeting agent. Most …
Panitumumab vs bevacizumab added to standard first-line chemotherapy and overall survival among patients with RAS wild-type, left-sided metastatic colorectal …
J Watanabe, K Muro, K Shitara, K Yamazaki… - Jama, 2023 - jamanetwork.com
Importance For patients withRASwild-type metastatic colorectal cancer, adding anti–
epidermal growth factor receptor (anti-EGFR) or anti–vascular endothelial growth factor (anti …
epidermal growth factor receptor (anti-EGFR) or anti–vascular endothelial growth factor (anti …
Pembrolizumab plus axitinib versus sunitinib monotherapy as first-line treatment of advanced renal cell carcinoma (KEYNOTE-426): extended follow-up from a …
T Powles, ER Plimack, D Soulières, T Waddell… - The Lancet …, 2020 - thelancet.com
Background The first interim analysis of the KEYNOTE-426 study showed superior efficacy
of pembrolizumab plus axitinib over sunitinib monotherapy in treatment-naive, advanced …
of pembrolizumab plus axitinib over sunitinib monotherapy in treatment-naive, advanced …
[HTML][HTML] Prognostic and predictive value of primary tumour side in patients with RAS wild-type metastatic colorectal cancer treated with chemotherapy and EGFR …
Background There is increasing evidence that metastatic colorectal cancer (mCRC) is a
genetically heterogeneous disease and that tumours arising from different sides of the colon …
genetically heterogeneous disease and that tumours arising from different sides of the colon …
Modern therapeutic approaches for the treatment of malignant liver tumours
H Petrowsky, R Fritsch, M Guckenberger… - Nature reviews …, 2020 - nature.com
Malignant liver tumours include a wide range of primary and secondary tumours. Although
surgery remains the mainstay of curative treatment, modern therapies integrate a variety of …
surgery remains the mainstay of curative treatment, modern therapies integrate a variety of …
FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab for metastatic colorectal cancer (FIRE-3): a post-hoc analysis of tumour dynamics in the final RAS wild-type …
S Stintzing, DP Modest, L Rossius, MM Lerch… - The Lancet …, 2016 - thelancet.com
Background FIRE-3 compared first-line 5-fluorouracil, leucovorin, and irinotecan (FOLFIRI)
plus cetuximab with FOLFIRI plus bevacizumab in patients with KRAS exon 2 wild-type …
plus cetuximab with FOLFIRI plus bevacizumab in patients with KRAS exon 2 wild-type …
FOLFIRI plus cetuximab or bevacizumab for advanced colorectal cancer: final survival and per-protocol analysis of FIRE-3, a randomised clinical trial
V Heinemann, LF von Weikersthal, T Decker… - British journal of …, 2021 - nature.com
Background Cetuximab plus FOLFIRI improved overall survival compared with bevacizumab
plus FOLFIRI in KRAS wild-type metastatic colorectal cancer (mCRC) in FIRE-3, but no …
plus FOLFIRI in KRAS wild-type metastatic colorectal cancer (mCRC) in FIRE-3, but no …
Multidisciplinary approach of liver metastases from colorectal cancer
R Adam, Y Kitano - Annals of gastroenterological surgery, 2019 - Wiley Online Library
Colorectal cancer liver metastases (CRLM) represent most of the causes of death in patients
with colorectal cancer. Surgical resection is the only treatment that can provide the …
with colorectal cancer. Surgical resection is the only treatment that can provide the …
Deep learning for the prediction of early on-treatment response in metastatic colorectal cancer from serial medical imaging
In current clinical practice, tumor response assessment is usually based on tumor size
change on serial computerized tomography (CT) scan images. However, evaluation of tumor …
change on serial computerized tomography (CT) scan images. However, evaluation of tumor …