TMEM65 promotes gastric tumorigenesis by targeting YWHAZ to activate PI3K-Akt-mTOR pathway and is a therapeutic target

L Shi, X Wang, S Guo, H Gou, H Shang, X Jiang, C Wei… - Oncogene, 2024 - nature.com
Copy number alterations are crucial for the development of gastric cancer (GC). Here, we
identified Transmembrane Protein 65 (TMEM65) amplification by genomic hybridization …

miR‑29b‑3p inhibits 22Rv1 prostate cancer cell proliferation through the YWHAE/BCL‑2 regulatory axis

J Zhao, X Ma, H Xu - Oncology letters, 2022 - spandidos-publications.com
Prostate cancer (PCa) is one of the most common malignant tumours in the world and
seriously affects health of men. Studies have shown that microRNA (miR)‑29b‑3p and …

Procoxacin bidirectionally inhibits osteoblastic and osteoclastic activity in bone and suppresses bone metastasis of prostate cancer

D Kong, C Ye, C Zhang, X Sun, F Wang… - Journal of Experimental …, 2023 - Springer
Background Bone is the most common site of metastasis of prostate cancer (PCa). PCa
invasion leads to a disruption of osteogenic-osteolytic balance and causes abnormal bone …

Deregulated 14-3-3ζ and methionine adenosyltransferase α1 interplay promotes liver cancer tumorigenesis in mice and humans

L Lu, J Zhang, W Fan, Y Li, J Wang, TWH Li… - Oncogene, 2021 - nature.com
Abstract Methionine adenosyltransferase 1A (MAT1A) is a tumor suppressor downregulated
in hepatocellular carcinoma and cholangiocarcinoma, two of the fastest rising cancers …

The survival analysis and oncogenic effects of CFP1 and 14-3-3 expression on gastric cancer

J Sun, Y Long, X Peng, D Xiao, J Zhou, Y Tao… - Cancer Cell …, 2019 - Springer
Background & aim Gastric cancer (GC) is the third-leading cause of cancer-related deaths.
We established a prospective database of patients with GC who underwent surgical …

miR-31-5p Regulates 14-3-3 ɛ to Inhibit Prostate Cancer 22RV1 Cell Survival and Proliferation via PI3K/AKT/Bcl-2 Signaling Pathway

J Zhao, H Xu, Z Duan, X Chen, Z Ao… - Cancer management …, 2020 - Taylor & Francis
Introduction Prostate cancer (PCa) is one of the most common malignancies, and almost all
patients with advanced PCa will develop castration-resistant prostate cancer (CRPC) after …