Scientists have long sought to characterize the pathophysiologic basis of schizophrenia and
develop biomarkers that could identify the illness. Extensive postmortem and in vivo …

Psychosis Psychosis is a syndrome embedded in several disorders, including schizophrenia
and bipolar disorder with psychotic features. Dopamine and glutamate are implicated in the …

This report calls on the nation—its leaders, its mental health research and service provision
agencies, its schools, its primary care medical systems, its community-based organizations …

Objective: Recent, large, randomized controlled trials (RCTs) showed no benefit of long-
acting injectable (LAI) antipsychotics over oral antipsychotics in preventing relapse in …

Originally published in February 2004. This guideline is more than 5 years old and has not
yet been updated to ensure that it reflects current knowledge and practice. In accordance …

Since the introduction of chlorpromazine and throughout the development of the new-
generation antipsychotic drugs (APDs) beginning with clozapine, the D 2 receptor has been …

New advances in the understanding of schizophrenia etiology, course, and treatment have
increased interest on the part of patients, families, advocates, and professionals in the …

Background: While long-acting injectable antipsychotics (LAIs) are hoped to reduce high
relapse rates in schizophrenia, recent randomized controlled trials (RCTs) challenged the …

The current state of the literature regarding psychosocial treatments for schizophrenia is
reviewed within the frameworks of the recovery model of mental health and the expanded …

OBJECTIVE: The duration of untreated psychosis may influence response to treatment,
reflecting a potentially malleable progressive pathological process. The authors reviewed …