Amyloid or amyloid-like fibrils represent a general class of nanomaterials that can be formed
from many different peptides and proteins. Although these structures have an important role …

The aggregation of proteins is of fundamental relevance in a number of daily phenomena,
as important and diverse as blood coagulation, medical diseases, or cooking an egg in the …

Protein fibrils resulting from assembly of proteins or peptides into long, insoluble, highly
ordered fibrillar structures are emerging as one of the fastest growing scientific areas, since …

Cell-penetrating peptides (CPPs) are a topical subject potentially exploitable for creating
nanotherapeutics for the delivery of bioactive loads. These compounds are often classified …

The delivery of therapeutic peptides and proteins to the central nervous system is the
biggest challenge when developing effective neuropharmaceuticals. The central issue is …

The human amniotic membrane (AM) is a tissue of fetal origin and has proven to be clinically
useful as a biomaterial in the management of various ocular surface disorders including …

Alzheimer's disease (AD) is the most common form of dementia and the sixth leading cause
of death in the United States. Plaques composed of aggregated amyloid-beta protein (Aβ) …

We have compared the protein profiles in plaques and tangles in the hippocampus of post-
mortem Alzheimer brains and in opaque and clear regions in the deep cortex of eye lenses …

The enzymatic cleavage of a peptide amphiphile (PA) is investigated. The self-assembly of
the cleaved products is distinct from that of the PA substrate. The PA C16-KKFFVLK is …

Amyloid formation plays a causative role in neurodegenerative diseases such as
Alzheimer's disease or Parkinson's disease. Soluble peptides form β-sheets that …