Macrophages play key roles in all phases of adult wound healing, which are inflammation,
proliferation, and remodeling. As wounds heal, the local macrophage population transitions …

The heme oxygenase-1 (HO-1) enzyme system remains an attractive therapeutic target for
the treatment of inflammatory conditions. HO-1, a cellular stress protein, serves a vital …

Nonhealing diabetic wounds are common complications for diabetic patients. Because
chronic hypoxia prominently delays wound healing, sustained oxygenation to alleviate …

INTRODUCTION The microbiota promotes the maturation and homeostasis of the immune
system, in part through the release of microbial products. Early-life microbial colonization …

Heme oxygenases are composed of two isozymes, Hmox1 and Hmox2, that catalyze the
degradation of heme to carbon monoxide (CO), ferrous iron, and biliverdin, the latter of …

The upregulation of heme oxygenase-1 (HO-1) is one of the most important mechanisms of
cell adaptation to stress. Indeed, the redox sensitive transcription factor Nrf2 is the pivotal …

Understanding the processes governing the ability of the heart to repair and regenerate after
injury is crucial for developing translational medical solutions. New avenues of exploration …

Epigallocatechin gallate (EGCG) is associated with various health benefits. In this review,
we searched current work about the effects of EGCG and its wound dressings on skin for …

Blood vessel formation is a fundamental process for the development of organism and tissue
regeneration. Of importance, angiogenesis occurring during postnatal development is …

Background Neovasculogenesis, vital for wound healing, gets compromised in diabetics
patients, which consequently delayed wound healing. Previous studies have shown …