Spinal cord repair: advances in biology and technology
G Courtine, MV Sofroniew - Nature medicine, 2019 - nature.com
Individuals with spinal cord injury (SCI) can face decades with permanent disabilities.
Advances in clinical management have decreased morbidity and improved outcomes, but …
Advances in clinical management have decreased morbidity and improved outcomes, but …
[HTML][HTML] Neurostimulation for stroke rehabilitation
Neurological injuries such as strokes can lead to important loss in motor function. Thanks to
neuronal plasticity, some of the lost functionality may be recovered over time. However, the …
neuronal plasticity, some of the lost functionality may be recovered over time. However, the …
An intracortical neuroprosthesis immediately alleviates walking deficits and improves recovery of leg control after spinal cord injury
M Bonizzato, M Martinez - Science translational medicine, 2021 - science.org
Most rehabilitation interventions after spinal cord injury (SCI) only target the sublesional
spinal networks, peripheral nerves, and muscles. However, mammalian locomotion is not a …
spinal networks, peripheral nerves, and muscles. However, mammalian locomotion is not a …
Repetitive transcranial magnetic stimulation of the brain after ischemic stroke: mechanisms from animal models
Y Xing, Y Zhang, C Li, L Luo, Y Hua, J Hu… - Cellular and Molecular …, 2023 - Springer
Stroke is a common cerebrovascular disease with high morbidity, mortality, and disability
worldwide. Post-stroke dysfunction is related to the death of neurons and impairment of …
worldwide. Post-stroke dysfunction is related to the death of neurons and impairment of …
[HTML][HTML] Functional electrical stimulation and the modulation of the axon regeneration program
Neural injury in mammals often leads to persistent functional deficits as spontaneous repair
in the peripheral nervous system (PNS) is often incomplete, while endogenous repair …
in the peripheral nervous system (PNS) is often incomplete, while endogenous repair …
[HTML][HTML] Transspinal stimulation increases motoneuron output of multiple segments in human spinal cord injury
LM Murray, M Knikou - PloS one, 2019 - journals.plos.org
Targeted neuromodulation strategies that strengthen neuronal activity are in great need for
restoring sensorimotor function after chronic spinal cord injury (SCI). In this study, we …
restoring sensorimotor function after chronic spinal cord injury (SCI). In this study, we …
[HTML][HTML] Neurophysiological changes after paired brain and spinal cord stimulation coupled with locomotor training in human spinal cord injury
TS Pulverenti, M Zaaya, M Grabowski… - Frontiers in …, 2021 - frontiersin.org
Neurophysiological changes that involve activity-dependent neuroplasticity mechanisms via
repeated stimulation and locomotor training are not commonly employed in research even …
repeated stimulation and locomotor training are not commonly employed in research even …
Brain and spinal cord paired stimulation coupled with locomotor training affects polysynaptic flexion reflex circuits in human spinal cord injury
TS Pulverenti, M Zaaya, M Knikou - Experimental brain research, 2022 - Springer
Neurorecovery from locomotor training is well established in human spinal cord injury (SCI).
However, neurorecovery resulting from combined interventions has not been widely studied …
However, neurorecovery resulting from combined interventions has not been widely studied …
[HTML][HTML] Brain and spinal cord paired stimulation coupled with locomotor training facilitates motor output in human spinal cord injury
TS Pulverenti, M Zaaya, E Grabowski… - Frontiers in …, 2022 - frontiersin.org
Combined interventions for neuromodulation leading to neurorecovery have gained great
attention by researchers to resemble clinical rehabilitation approaches. In this randomized …
attention by researchers to resemble clinical rehabilitation approaches. In this randomized …
[HTML][HTML] Using EMG to deliver lumbar dynamic electrical stimulation to facilitate cortico-spinal excitability
Background Potentiation of synaptic activity in spinal networks is reflected in the magnitude
of modulation of motor responses evoked by spinal and cortical input. After spinal cord …
of modulation of motor responses evoked by spinal and cortical input. After spinal cord …