A New Variant of Mutational and Polymorphic Signatures in the ERG11 Gene of Fluconazole-Resistant Candida albicans
AS Odiba, OA Durojaye, IM Ezeonu… - Infection and Drug …, 2022 - Taylor & Francis
Background Resistance to antifungal drugs for treating Candida infections remains a major
concern globally despite the range of medications available. Most of these drugs target key …
concern globally despite the range of medications available. Most of these drugs target key …
The natural anthraquinone dye purpurin exerts antibacterial activity by perturbing the FtsZ assembly
S Mahanty, K Rathinasamy - Bioorganic & Medicinal Chemistry, 2021 - Elsevier
There is an increasing demand to discover novel antibacterial drugs to counter the ever-
evolving genetic machinery of bacteria. The cell division protein FtsZ plays a vital role in …
evolving genetic machinery of bacteria. The cell division protein FtsZ plays a vital role in …
Efficient selective targeting of Candida CYP51 by oxadiazole derivatives designed from plant cuminaldehyde
Candida infection represents a global threat with associated high resistance and mortality
rate. Azoles such as the triazole drug fluconazole are the frontline therapy against invasive …
rate. Azoles such as the triazole drug fluconazole are the frontline therapy against invasive …
Pan‐azole‐resistant Meyerozyma guilliermondii clonal isolates harbouring a double F126L and L505F mutation in Erg11
J Moreau, T Noël, K Point, F Tewes, L Deroche… - Mycoses, 2024 - Wiley Online Library
Background Meyerozyma guilliermondii is a yeast species responsible for invasive fungal
infections. It has high minimum inhibitory concentrations (MICs) to echinocandins, the first …
infections. It has high minimum inhibitory concentrations (MICs) to echinocandins, the first …
[HTML][HTML] Integrated exploration of molecular structure, quantum chemical properties, molecular docking, and antioxidant activity of 4-(2-hydroxyanilino) pent-3-en-2 …
S Chahmana, F Benghanem, M Fellah, H Aityoucef… - Results in …, 2024 - Elsevier
Schiff bases are crucial intermediates in organic chemistry. They are used to introduce
carbon–nitrogen double bonds in organic molecules. In this study, 4-(2-hydroxyanilino) pent …
carbon–nitrogen double bonds in organic molecules. In this study, 4-(2-hydroxyanilino) pent …
[HTML][HTML] Repurposing vilanterol as a novel potential antifungal for Candida albicans: In-silico & in-vitro approach
SMU Prakash, MA Kabir - Medicine in Drug Discovery, 2022 - Elsevier
Candida albicans infects immune-compromised persons, and its resistance to antifungal
drugs has become a significant health concern, which causes a higher mortality rate …
drugs has become a significant health concern, which causes a higher mortality rate …
In-silico investigation and ADMET prediction of potential antifungal phytochemicals against lanosterol 14-alpha demethylase inhibitors
SA Shinde, MJ Mhetar, AG Parit… - Asian Journal of …, 2024 - indianjournals.com
Mycosis is a chronic infectious disorder caused by various fungi affecting about 5% of the
worldwide population. Pathogenesis involves the primary contact or inhalational roué for …
worldwide population. Pathogenesis involves the primary contact or inhalational roué for …
[PDF][PDF] Results in Chemistry
S Chahmana, F Benghanem, M Fellah, H Aityoucef… - researchgate.net
Schiff bases are crucial intermediates in organic chemistry. They are used to introduce
carbon–nitrogen double bonds in organic molecules. In this study, 4-(2-hydroxyanilino) pent …
carbon–nitrogen double bonds in organic molecules. In this study, 4-(2-hydroxyanilino) pent …
[PDF][PDF] Medicine in Drug Discovery
SMU Prakash, MA Kabir - researchgate.net
Candida albicans infects immune‐compromised persons, and its resistance to antifungal
drugs has become a significant health concern, which causes a higher mortality rate …
drugs has become a significant health concern, which causes a higher mortality rate …