ABO blood group antigens and differential glycan expression: perspective on the evolution of common human enzyme deficiencies

RP Jajosky, SC Wu, L Zheng, AN Jajosky, PG Jajosky… - Iscience, 2023 - cell.com
Enzymes catalyze biochemical reactions and play critical roles in human health and
disease. Enzyme variants and deficiencies can lead to variable expression of glycans, which …

Antibody-Mediated Rejection in Lung Transplantation: Diagnosis and Therapeutic Armamentarium in a 21st Century Perspective

J Messika, N Belousova, F Parquin… - Transplant …, 2024 - frontierspartnerships.org
Humoral immunity is a major waypoint towards chronic allograft dysfunction in lung
transplantation (LT) recipients. Though allo-immunization and antibody-mediated rejection …

Set up for failure: pre-existing autoantibodies in lung transplant

A McQuiston, A Emtiazjoo, P Angel, T Machuca… - Frontiers in …, 2021 - frontiersin.org
Lung transplant patients have the lowest long-term survival rates compared to other solid
organ transplants. The complications after lung transplantation such as primary graft …

[HTML][HTML] Distinct Non-Human Leukocyte Antigen Antibody Signatures Correlate with Endothelial Crossmatch Status in Lung and Renal Transplant Recipients

F Alhamdan, A Coppolino, A Sheikh, A Miele… - International Journal of …, 2024 - mdpi.com
Non-HLA antibodies against heterogeneous targets on endothelial cells have been
associated with allograft injuries. The endothelial cell crossmatch (ECXM) is used in the …

The impact of non-HLA antibodies on outcomes after lung transplantation and implications for therapeutic approaches

RR Hachem - Human Immunology, 2019 - Elsevier
The role of donor-specific antibodies (DSA) to mismatched human leukocyte antigens (HLA)
in lung allograft rejection has been recognized over the past 20 years. During this time, there …

Rejection and vaccination in lung transplant recipients

S Liu - 2024 - research.rug.nl
This thesis addresses two pivotal issues in lung transplant recipients (LTRs): the detection of
biomarkers for acute rejection (AR) and an investigation into the immunogenicity of the …