Merkel cell carcinoma (MCC) is a rare but highly aggressive skin cancer with
neuroendocrine features. MCC pathogenesis is associated with either the presence of …

Merkel cell carcinoma (MCC) is an aggressive neuroendocrine carcinoma of the skin with
two distinct etiologies. Clonal integration of Merkel cell polyomavirus DNA into the tumor …

Viruses are the cause of approximately 15% of all human cancers. Both RNA and DNA
human tumor viruses have been identified, with Merkel cell polyomavirus being the most …

Merkel cell carcinoma (MCC) frequently contains integrated copies of Merkel cell
polyomavirus DNA that express a truncated form of Large T antigen (LT) and an intact Small …

Merkel cell carcinoma (MCC) is a highly aggressive, often lethal neuroendocrine cancer. Its
carcinogenesis may be either caused by the clonal integration of the Merkel cell …

Highlights•MCPyV infection is highly prevalent in the general population.•In elderly and
immunosuppressed individuals, MCPyV can cause Merkel cell carcinoma.•LT and sT …

Merkel cell polyomavirus (MCV) contributes to approximately 80% of all Merkel cell
carcinomas (MCCs), a highly aggressive neuroendocrine carcinoma of the skin. MCV …

Merkel cell polyomavirus (MCPyV) causes the highly aggressive and relatively rare skin
cancer known as Merkel cell carcinoma (MCC). MCPyV also causes a lifelong yet relatively …

Merkel cell carcinoma is a rare neuroendocrine carcinoma that typically appears in sun‐
exposed areas of the elderly. It has a poor prognosis and with its incidence projected to …

Interference with tumor suppressor pathways by polyomavirus-encoded tumor antigens (T-
Ags) can result in transformation. Consequently, it is thought that T-Ags encoded by Merkel …