Organocatalysis in inert C–H bond functionalization

Y Qin, L Zhu, S Luo - Chemical reviews, 2017 - ACS Publications
As two coexisting and fast-growing research fields in modern synthetic chemistry, the
merging of organocatalysis and C–H bond functionalization is well foreseeable, and the joint …

Transition-metal-free coupling reactions

CL Sun, ZJ Shi - Chemical reviews, 2014 - ACS Publications
Transition-metal-catalyzed reactions have been studied since the very beginning of the past
century and represent a great success in organic chemistry, along with the birth and growth …

Recent development of direct asymmetric functionalization of inert C–H bonds

C Zheng, SL You - RSC advances, 2014 - pubs.rsc.org
The area of direct asymmetric functionalization of inert C–H bonds has attracted
considerable attention in recent years. To realize this type of challenging but promising …

Cyclization Cascades via N-Amidyl Radicals toward Highly Functionalized Heterocyclic Scaffolds

N Fuentes, W Kong… - Journal of the …, 2015 - ACS Publications
The addition of a variety of radicals to the double bond of N-(arylsulfonyl) acrylamides can
trigger cyclization/aryl migration/desulfonylation cascades via amidyl radical intermediates …

Dioxygen-triggered oxidative radical reaction: direct aerobic difunctionalization of terminal alkynes toward β-keto sulfones

Q Lu, J Zhang, G Zhao, Y Qi, H Wang… - Journal of the American …, 2013 - ACS Publications
An unprecedented dioxygen-triggered oxidative radical process was explored using
dioxygen as the solely terminal oxidant, realizing aerobic oxidaitve difunctionalization of …

Recent advances in transition-metal catalyzed reactions using molecular oxygen as the oxidant

Z Shi, C Zhang, C Tang, N Jiao - Chemical Society Reviews, 2012 - pubs.rsc.org
For green and sustainable chemistry, molecular oxygen is considered as an ideal oxidant
due to its natural, inexpensive, and environmentally friendly characteristics, and therefore …

A Comparative Mechanistic Study of Cu-Catalyzed Oxidative Coupling Reactions with N-Phenyltetrahydroisoquinoline

E Boess, C Schmitz, M Klussmann - Journal of the American …, 2012 - ACS Publications
A comparative mechanistic study of Cu-catalyzed oxidative coupling reactions of N-
phenyltetrahydroisoquinoline with different nucleophiles was conducted. Two previously …

Asymmetric dearomatization of indole derivatives with N‐hydroxycarbamates enabled by photoredox catalysis

YZ Cheng, QR Zhao, X Zhang, SL You - Angewandte Chemie, 2019 - Wiley Online Library
Dearomatization of indoles provides efficient synthetic routes for substituted indolines. In
most cases, indoles serve as nucleophiles. Reported here is an asymmetric dearomatization …

Cu-catalyzed esterification reaction via aerobic oxygenation and C–C bond cleavage: an approach to α-ketoesters

C Zhang, P Feng, N Jiao - Journal of the American Chemical …, 2013 - ACS Publications
The Cu-catalyzed novel aerobic oxidative esterification reaction of 1, 3-diones for the
synthesis of α-ketoesters has been developed. This method combines C–C σ-bond …

A Versatile C–H Functionalization of Tetrahydroisoquinolines Catalyzed by Iodine at Aerobic Conditions

J Dhineshkumar, M Lamani, K Alagiri, KR Prabhu - Organic letters, 2013 - ACS Publications
A versatile aerobic catalytic system (I2 and O2/TBHP) for C–H functionalization is reported.
This CDC (cross-dehydrogentive coupling) reaction is compatible with a large number of …