Mechanisms, applications, and challenges of insect RNA interference

KY Zhu, SR Palli - Annual review of entomology, 2020 - annualreviews.org
The RNA interference (RNAi) triggered by short/small interfering RNA (siRNA) was
discovered in nematodes and found to function in most living organisms. RNAi has been …

[HTML][HTML] Double-stranded RNA technology to control insect pests: current status and challenges

O Christiaens, S Whyard, AM Vélez… - Frontiers in Plant …, 2020 - frontiersin.org
Exploiting the RNA interference (RNAi) gene mechanism to silence essential genes in pest
insects, leading to toxic effects, has surfaced as a promising new control strategy in the past …

[HTML][HTML] Visualization of the process of a nanocarrier-mediated gene delivery: stabilization, endocytosis and endosomal escape of genes for intracellular spreading

Z Ma, Y Zheng, Z Chao, H Chen, Y Zhang… - Journal of …, 2022 - Springer
Nanoparticles have been widely applied as gene carrier for improving RNA interference
(RNAi) efficiency in medical and agricultural fields. However, the mechanism and delivery …

RNA interference technology in crop protection against arthropod pests, pathogens and nematodes

M Zotti, EA Dos Santos, D Cagliari… - Pest management …, 2018 - Wiley Online Library
Scientists have made significant progress in understanding and unraveling several aspects
of double‐stranded RNA (dsRNA)‐mediated gene silencing during the last two decades …

[HTML][HTML] RNAi efficiency, systemic properties, and novel delivery methods for pest insect control: what we know so far

MR Joga, MJ Zotti, G Smagghe… - Frontiers in physiology, 2016 - frontiersin.org
In recent years, the research on the potential of using RNA interference (RNAi) to suppress
crop pests has made an outstanding growth. However, given the variability of RNAi …

Molecular mechanisms influencing efficiency of RNA interference in insects

AMW Cooper, K Silver, J Zhang, Y Park… - Pest management …, 2019 - Wiley Online Library
RNA interference (RNAi) is an endogenous, sequence‐specific gene‐silencing mechanism
elicited by small RNA molecules. RNAi is a powerful reverse genetic tool, and is currently …

Next-generation insect-resistant plants: RNAi-mediated crop protection

J Zhang, SA Khan, DG Heckel, R Bock - Trends in biotechnology, 2017 - cell.com
Plant-mediated RNA interference (RNAi) shows great potential in crop protection. It relies on
plants stably expressing double-stranded RNAs (dsRNAs) that target essential genes in pest …

Spray method application of transdermal dsRNA delivery system for efficient gene silencing and pest control on soybean aphid Aphis glycines

S Yan, J Qian, C Cai, Z Ma, J Li, M Yin, B Ren… - Journal of Pest …, 2020 - Springer
RNA interference (RNAi) has been recognized as a novel and safe strategy in pest
management due to its high sequence-dependent specificity. However, the existing dsRNA …

[HTML][HTML] RNA-based technologies for insect control in plant production

S Liu, M Jaouannet, DMA Dempsey, J Imani… - Biotechnology …, 2020 - Elsevier
RNA interference (RNAi) is a biological process in which small RNA (sRNA) molecules
sequence-specifically silence gene expression at the transcriptional or post-transcriptional …

[HTML][HTML] Extracellular vesicles—connecting kingdoms

E Woith, G Fuhrmann, MF Melzig - International journal of molecular …, 2019 - mdpi.com
It is known that extracellular vesicles (EVs) are shed from cells of almost every type of cell or
organism, showing their ubiquity in all empires of life. EVs are defined as naturally released …