Pancreatic cancer is a highly malignant and incurable disease, characterized by its
aggressive nature and high fatality rate. The most common type is pancreatic ductal …

The disease heterogeneity and little therapeutic progress in neurodegenerative diseases
justify the need for novel and effective drug discovery approaches. Drug repurposing is an …

Individuals diagnosed with cancer often turn to the use of herbal remedies with the intention
of treating and ameliorating the condition, impeding the progression of metastasis …

Lack of durable response to cytotoxic chemotherapy is a major contributor to the dismal
outcomes seen in pancreatic ductal adenocarcinoma (PDAC). Extensive tumor desmoplasia …

Purpose GAS41 is a YEATS domain protein that binds to acetylated histone H3 to promote
the chromatin deposition of H2A. Z in non-small cell lung cancer. The role of GAS41 in …

Several arylamide-based antiproliferative agents are known and some of them are currently
FDA-approved anticancer drugs. Provoked by the need to fill the existing room with new …

As the incidence of pancreatic ductal adenocarcinoma (PDAC) continues to grow, so does
the need for new strategies for treatment. One such area being evaluated is cryoablation …

This review highlights current treatments, limitations, and pitfalls in the management of
pancreatic cancer and discusses current research in novel targets and drug development to …

Introduction The aim of this review was to characterize the second-and later-line (≥ 2L)
treatment landscape for patients with metastatic pancreatic ductal adenocarcinoma …

Pancreatic cancer (PC) is one of the most malignant tumors with a dismal survival rate, this
is primarily due to inevitable chemoresistance. Dysfunctional tyrosine kinases (TKs) and …