The term acanthocytosis is derived from the Greek for" thorn" and is used to describe a
peculiar spiky appearance of erythrocytes. Acanthocytosis is found to be associated with at …

Two membrane proteins express the antigens that comprise the Kell blood group system. A
single antigen, Kx, is carried on XK, a 440-amino acid protein that spans the membrane 10 …

McLeod syndrome is caused by mutations of XK, an X‐chromosomal gene of unknown
function. Originally defined as a peculiar Kell blood group variant, the disease affects …

Loss-of-function mutations in the gene ced-8 lead to the late appearance of cell corpses
during embryonic development in C. elegans. ced-8 functions downstream of or in parallel to …

In recent years, advances in biochemistry and molecular genetics have contributed to
establishing the structure of the genes and proteins from most of the 23 blood group systems …

The molecular basis of different Kell blood group phenotypes is reviewed. Sequence
analysis of the Kell gene (KEL) established that single base substitutions, resulting in amino …

Over 250 blood group determinants are known and most of these are located on integral red
cell proteins and glycoproteins. The functions of some of these structures are known: Diego …

The high‐frequency blood group antigen Oka is carried on a red cell membrane
glycoprotein (gp) of 35–69 kDa that is widely distributed on malignant cells of different …

The X‐linked McLeod syndrome is defined by absent Kx red blood cell antigen and weak
expression of Kell antigens, and this constellation may be accidentally detected in routine …

BACKGROUND: The X‐linked McLeod neuroacanthocytosis syndrome is a multisystem
disorder with hematologic, neuromuscular, and central nervous system (CNS) …