[HTML][HTML] Immunomodulation—a general review of the current state-of-the-art and new therapeutic strategies for targeting the immune system

M Strzelec, J Detka, P Mieszczak… - Frontiers in …, 2023 - frontiersin.org
In recent years, there has been a tremendous development of biotechnological,
pharmacological, and medical techniques which can be implemented in the functional …

[HTML][HTML] MSCs-derived exosomes: cell-secreted nanovesicles with regenerative potential

A Marote, FG Teixeira, B Mendes-Pinheiro… - Frontiers in …, 2016 - frontiersin.org
Exosomes are membrane-enclosed nanovesicles (30–150 nm) that shuttle active cargoes
between different cells. These tiny extracellular vesicles have been recently isolated from …

[HTML][HTML] The stem cell secretome and its role in brain repair

D Drago, C Cossetti, N Iraci, E Gaude, G Musco… - Biochimie, 2013 - Elsevier
Compelling evidence exists that non-haematopoietic stem cells, including mesenchymal
(MSCs) and neural/progenitor stem cells (NPCs), exert a substantial beneficial and …

Umbilical cord mesenchymal stem cells: the new gold standard for mesenchymal stem cell-based therapies?

R El Omar, J Beroud, JF Stoltz, P Menu… - … Engineering Part B …, 2014 - liebertpub.com
Due to their self-renewal capacity, multilineage differentiation potential, paracrine effects,
and immunosuppressive properties, mesenchymal stromal cells (MSCs) are an attractive …

Mesenchymal stem cells secretome: a new paradigm for central nervous system regeneration?

FG Teixeira, MM Carvalho, N Sousa… - Cellular and Molecular …, 2013 - Springer
The low regeneration potential of the central nervous system (CNS) represents a challenge
for the development of new therapeutic strategies. Mesenchymal stem cells (MSCs) have …

Unveiling the differences of secretome of human bone marrow mesenchymal stem cells, adipose tissue-derived stem cells, and human umbilical cord perivascular …

AO Pires, B Mendes-Pinheiro, FG Teixeira… - Stem cells and …, 2016 - liebertpub.com
The use of human mesenchymal stem cells (hMSCs) has emerged as a possible therapeutic
strategy for CNS-related conditions. Research in the last decade strongly suggests that MSC …

[HTML][HTML] Mesenchymal stem cells from human umbilical cord express preferentially secreted factors related to neuroprotection, neurogenesis, and angiogenesis

JY Hsieh, HW Wang, SJ Chang, KH Liao, IH Lee… - PloS one, 2013 - journals.plos.org
Mesenchymal stem cells (MSCs) are promising tools for the treatment of diseases such as
infarcted myocardia and strokes because of their ability to promote endogenous …

[HTML][HTML] Human mesenchymal stem cell secretome driven T cell immunomodulation is IL-10 dependent

MT Shephard, MM Merkhan, NR Forsyth - International Journal of …, 2022 - mdpi.com
The Human Mesenchymal Stem Cell (hMSC) secretome has pleiotropic effects
underpinning its therapeutic potential. hMSC serum-free conditioned media (SFCM) …

Proteomic techniques for characterisation of mesenchymal stem cell secretome

HK Skalnikova - Biochimie, 2013 - Elsevier
Mesenchymal stem cells (MSCs) are multipotent cells with a substantial potential in human
regenerative medicine due to their ability to migrate to sites of injury, capability to suppress …

Hydrogels and cell based therapies in spinal cord injury regeneration

RC Assunção-Silva, ED Gomes, N Sousa… - Stem cells …, 2015 - Wiley Online Library
Spinal cord injury (SCI) is a central nervous system‐(CNS‐) related disorder for which there
is yet no successful treatment. Within the past several years, cell‐based therapies have …