Molecular evolution of antifungal drug resistance
The fungal pathogens Candida albicans, Cryptococcus neoformans, and Aspergillus
fumigatus have transitioned from a rare curiosity to a leading cause of human mortality. The …
fumigatus have transitioned from a rare curiosity to a leading cause of human mortality. The …
Antimicrobial resistance and virulence: a successful or deleterious association in the bacterial world?
Hosts and bacteria have coevolved over millions of years, during which pathogenic bacteria
have modified their virulence mechanisms to adapt to host defense systems. Although the …
have modified their virulence mechanisms to adapt to host defense systems. Although the …
Antibiotic resistance: moving from individual health norms to social norms in one health and global health
Antibiotic resistance is a problem for human health, and consequently, its study had been
traditionally focused toward its impact for the success of treating human infections in …
traditionally focused toward its impact for the success of treating human infections in …
Bacterial diversity and antibiotic resistance in water habitats: searching the links with the human microbiome
I Vaz-Moreira, OC Nunes… - FEMS microbiology …, 2014 - academic.oup.com
Water is one of the most important bacterial habitats on Earth. As such, water represents
also a major way of dissemination of bacteria between different environmental …
also a major way of dissemination of bacteria between different environmental …
Antiviral drug resistance as an adaptive process
KK Irwin, N Renzette, TF Kowalik, JD Jensen - Virus evolution, 2016 - academic.oup.com
Antiviral drug resistance is a matter of great clinical importance that, historically, has been
investigated mostly from a virological perspective. Although the proximate mechanisms of …
investigated mostly from a virological perspective. Although the proximate mechanisms of …
Evolutionary consequences of drug resistance: shared principles across diverse targets and organisms
D Hughes, DI Andersson - Nature Reviews Genetics, 2015 - nature.com
Drug therapy has a crucial role in the treatment of viral, bacterial, fungal and protozoan
infections, as well as the control of human cancer. The success of therapy is being …
infections, as well as the control of human cancer. The success of therapy is being …
A state-of-art review on multi-drug resistant pathogens in foods of animal origin: risk factors and mitigation strategies
F Pérez-Rodríguez, B Mercanoglu Taban - Frontiers in Microbiology, 2019 - frontiersin.org
Most of the foodborne microbial diseases are linked to foods of animal origin such as milk,
meat, and poultry. Nowadays, the presence of multi-drug resistant (MDR) pathogens in …
meat, and poultry. Nowadays, the presence of multi-drug resistant (MDR) pathogens in …
Effect of antibiotic use and composting on antibiotic resistance gene abundance and resistome risks of soils receiving manure-derived amendments
Manure-derived amendments are commonly applied to soil, raising questions about whether
antibiotic use in livestock could influence the soil resistome (collective antibiotic resistance …
antibiotic use in livestock could influence the soil resistome (collective antibiotic resistance …
Multidisciplinary approach to prostatitis
The modern clinical research on prostatitis started with the work of Stamey and coworkers
who developed the basic principles we are still using. They established the segmented …
who developed the basic principles we are still using. They established the segmented …
Population biological principles of drug-resistance evolution in infectious diseases
The emergence of resistant pathogens in response to selection pressure by drugs and their
possible disappearance when drug use is discontinued are evolutionary processes common …
possible disappearance when drug use is discontinued are evolutionary processes common …