Abstract Background Antiemetic agent Meclizine HCl, widely prescribed in vertigo, is
available only in immediate release dosage forms. The approved therapeutic dose and …

Background The study was to develop an extended release (ER) encapsulated and
compacted pellets of Atenolol using hydrophobic (wax based and polymeric based) and …

According to the drug discovery, approximately 40% of the new chemical entities show poor
bioavailability due to their low aqueous solubility. In order to increase the solubility of the …

The objective of this study was to prepare sustained-release coated pellets of loxoprofen
sodium by extrusion–spheronization technique and to assess the coating application of ethyl …

The study was aimed to prolong the antispastic effect of a highly soluble drug Eperisone HC
l by osmotic drug delivery technology. Oral osmotically controlled release formulations of …

The objective of this study was to prepare ibuprofen enteric-coated sustained-release pellets
(IB-SRPs) and codeine phosphate immediate-release pellets (CP-IRPs) to play a synergistic …

Arsenic trioxide (ATO) is first-line drug for acute promyelocytic leukemia. Clinically, the
continuously slow intravenous infusion is adopted to maintain effective blood concentration …

The objective was to develop eperisone HCl sustained-release pellets through extrusion
spheronization technique and to determine the influence of different hydrophobic (polymeric …

The study was aimed to synthesize and characterize effective sustained release polymeric
microspheres of sulfasalazine and dexamethasone by using okra gum and hydroxypropyl …

Objective: In this study, pharmacokinetics (PKs) and bioavailability of newly developed
extended release (ER) Itopride HCl 150 mg encapsulated ER pellets (test) and 150 mg …