Carotid body chemoreceptors: physiology, pathology, and implications for health and disease
R Iturriaga, J Alcayaga, MW Chapleau… - Physiological …, 2021 - journals.physiology.org
The carotid body (CB) is the main peripheral chemoreceptor for arterial respiratory gases O2
and CO2 and pH, eliciting reflex ventilatory, cardiovascular, and humoral responses to …
and CO2 and pH, eliciting reflex ventilatory, cardiovascular, and humoral responses to …
Metabolic dysfunction in OSA: Is there something new under the sun?
The growing number of patients with obstructive sleep apnea is challenging healthcare
systems worldwide. Obstructive sleep apnea is characterized by chronic intermittent …
systems worldwide. Obstructive sleep apnea is characterized by chronic intermittent …
On the origins of sleep disordered breathing, cardiorespiratory and metabolic dysfunction: which came first, the chicken or the egg?
Sleep disordered breathing (SDB) is a complex, sex specific and highly heterogeneous
group of respiratory disorders. Nevertheless, sleep fragmentation and repeated fluctuations …
group of respiratory disorders. Nevertheless, sleep fragmentation and repeated fluctuations …
Carotid body contribution to the physio‐pathological consequences of intermittent hypoxia: Role of nitro‐oxidative stress and inflammation
R Iturriaga - The Journal of Physiology, 2023 - Wiley Online Library
Obstructive sleep apnoea (OSA), characterized by chronic intermittent hypoxia (CIH), is
considered to be an independent risk for hypertension. The pathological cardiorespiratory …
considered to be an independent risk for hypertension. The pathological cardiorespiratory …
Carotid body inflammation: role in hypoxia and in the anti-inflammatory reflex
Emergent evidence indicates that the carotid body (CB) chemoreceptor may sense systemic
inflammatory molecules and is an afferent arm of the anti-inflammatory reflex. Moreover, a …
inflammatory molecules and is an afferent arm of the anti-inflammatory reflex. Moreover, a …
Role of the Autonomic Nervous System in the Hemodynamic Response to Hyperinsulinemia—Implications for Obesity and Insulin Resistance
Abstract Purpose of Review Herein, we summarize recent advances which provide new
insights into the role of the autonomic nervous system in the control of blood flow and blood …
insights into the role of the autonomic nervous system in the control of blood flow and blood …
Translating carotid body function into clinical medicine
R Iturriaga - The Journal of physiology, 2018 - Wiley Online Library
The carotid body (CB) is considered the main O2 chemoreceptor, which contributes to
cardiorespiratory homeostasis and ventilatory acclimatization. In clinical medicine, the most …
cardiorespiratory homeostasis and ventilatory acclimatization. In clinical medicine, the most …
GABA dramatically improves glucose tolerance in streptozotocin-induced diabetic rats fed with high-fat diet
Skeletal muscle, hepatic insulin resistance, and beta cell dysfunction are the characteristic
pathophysiological features of type 2 diabetes mellitus. GABA has an important role in …
pathophysiological features of type 2 diabetes mellitus. GABA has an important role in …
Carotid body chemosensitivity: early biomarker of dysmetabolism in humans
JP Cunha-Guimaraes, MP Guarino… - European Journal of …, 2020 - academic.oup.com
Abstract Objective The carotid bodies (CBs) are peripheral chemoreceptor organs
classically described as being O2 sensors, which are increasingly emerging as core players …
classically described as being O2 sensors, which are increasingly emerging as core players …
[HTML][HTML] A2 adenosine receptors mediate whole-body insulin sensitivity in a prediabetes animal model: primary effects on skeletal muscle
Epidemiological studies showed that chronic caffeine intake decreased the risk of type 2
diabetes. Previously, we described that chronic caffeine intake prevents and reverses insulin …
diabetes. Previously, we described that chronic caffeine intake prevents and reverses insulin …