The vast complexity of primary open angle glaucoma: disease genes, risks, molecular mechanisms and pathobiology
SF Janssen, TGMF Gorgels, WD Ramdas… - Progress in retinal and …, 2013 - Elsevier
Primary open angle glaucoma (POAG) is a complex progressive optic nerve neuropathy
triggered by both environmental and genetic risk factors. Several ocular tissues, including …
triggered by both environmental and genetic risk factors. Several ocular tissues, including …
Genetics in Keratoconus: where are we?
Y Bykhovskaya, B Margines, YS Rabinowitz - Eye and Vision, 2016 - Springer
Keratoconus (KC) is a non-inflammatory thinning and protrusion of the cornea in which the
cornea assumes a conical shape. Complex etiology of this condition at present remains an …
cornea assumes a conical shape. Complex etiology of this condition at present remains an …
Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus
Central corneal thickness (CCT) is associated with eye conditions including keratoconus
and glaucoma. We performed a meta-analysis on> 20,000 individuals in European and …
and glaucoma. We performed a meta-analysis on> 20,000 individuals in European and …
[HTML][HTML] Large-scale whole-genome sequencing of three diverse Asian populations in Singapore
Underrepresentation of Asian genomes has hindered population and medical genetics
research on Asians, leading to population disparities in precision medicine. By whole …
research on Asians, leading to population disparities in precision medicine. By whole …
Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI
BFJ Verhaaren, S Debette, JC Bis… - Circulation …, 2015 - Am Heart Assoc
Background—The burden of cerebral white matter hyperintensities (WMH) is associated with
an increased risk of stroke, dementia, and death. WMH are highly heritable, but their genetic …
an increased risk of stroke, dementia, and death. WMH are highly heritable, but their genetic …
A large multi-ethnic genome-wide association study identifies novel genetic loci for intraocular pressure
H Choquet, KK Thai, J Yin, TJ Hoffmann… - Nature …, 2017 - nature.com
Elevated intraocular pressure (IOP) is a major risk factor for glaucoma, a leading cause of
blindness. IOP heritability has been estimated to up to 67%, and to date only 11 IOP loci …
blindness. IOP heritability has been estimated to up to 67%, and to date only 11 IOP loci …
Genetic aspects of keratoconus: a literature review exploring potential genetic contributions and possible genetic relationships with comorbidities
E Loukovitis, K Sfakianakis, P Syrmakesi… - Ophthalmology and …, 2018 - Springer
Introduction Keratoconus (KC) is a complex, genetically heterogeneous, multifactorial
degenerative disorder that is accompanied by corneal ectasia which usually progresses …
degenerative disorder that is accompanied by corneal ectasia which usually progresses …
The thick and thin of the central corneal thickness in glaucoma
GW Belovay, I Goldberg - Eye, 2018 - nature.com
Central corneal thickness (CCT) is an important parameter in the assessment of any
potential glaucoma patient. While it affects prognosis in ocular hypertension, its value in …
potential glaucoma patient. While it affects prognosis in ocular hypertension, its value in …
[HTML][HTML] The genetics of keratoconus: a review
J Wheeler, MA Hauser, NA Afshari… - Microscopy (Oxford …, 2012 - ncbi.nlm.nih.gov
Keratoconus is the most common ectatic disorder of the corneal. Genetic and environmental
factors may contribute to its pathogenesis. The focus of this article is to summarize current …
factors may contribute to its pathogenesis. The focus of this article is to summarize current …
Central corneal thickness in glaucoma
Central corneal thickness in glaucoma : Current Opinion in Ophthalmology Central corneal
thickness in glaucoma : Current Opinion in Ophthalmology Log in or Register Subscribe to …
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