Human pathogenic spirochetes causing Lyme disease belong to the Borrelia burgdorferi
sensu lato complex. Borrelia burgdorferi organisms are extracellular pathogens transmitted …

Borrelia burgdorferi, the spirochete that causes Lyme disease, is maintained in nature via an
enzootic cycle that comprises a tick vector and a vertebrate host. Transmission from the tick …

ABSTRACT A major obstacle to studying the functions of particular gene products in the
mouse-tick infectious cycle of Borrelia burgdorferi has been an inability to knock out genes …

Borrelia burgdorferi is the etiologic agent of Lyme disease, the most prevalent arthropod-
borne disease in the United States. The genome of the type strain, B31, consists of a …

Borrelia burgdorferi (Bb) adapts to its arthropod and mammalian hosts by altering its
transcriptional and antigenic profiles in response to environmental signals associated with …

Borrelia burgdorferi, a spirochaete that causes Lyme borreliosis, contains 21 linear and
circular plasmids thought to be important for survival in mammals or ticks. Our results …

Lyme disease is a tick-borne infection that can lead to chronic, debilitating problems if not
recognized or treated appropriately. Borrelia burgdorferi, the causative agent of Lyme …

ABSTRACT The Lyme disease spirochete, Borrelia burgdorferi, is capable of infecting a
wide variety of vertebrates. This broad host range implies that B. burgdorferi possesses the …

The Lyme disease spirochete persists in nature through cycles between ticks and
vertebrates. Although the spirochete interacts with numerous, distinct tissues and …

Lyme disease (LD) has become the most common vector-borne illness in the northern
hemisphere. The causative agent, Borrelia burgdorferi sensu lato, is capable of establishing …