Rational design of biomaterials to potentiate cancer thermal therapy

Y Zhu, Q Li, C Wang, Y Hao, N Yang, M Chen… - Chemical …, 2023 - ACS Publications
Cancer thermal therapy, also known as hyperthermia therapy, has long been exploited to
eradicate mass lesions that are now defined as cancer. With the development of …

Magnetic nanoparticles and clusters for magnetic hyperthermia: Optimizing their heat performance and developing combinatorial therapies to tackle cancer

H Gavilán, SK Avugadda… - Chemical Society …, 2021 - pubs.rsc.org
Magnetic hyperthermia (MHT) is a therapeutic modality for the treatment of solid tumors that
has now accumulated more than 30 years of experience. In the ongoing MHT clinical trials …

[HTML][HTML] Heat shock proteins: a review of the molecular chaperones for plant immunity

CJ Park, YS Seo - The plant pathology journal, 2015 - ncbi.nlm.nih.gov
As sessile organisms, plants are exposed to persistently changing stresses and have to be
able to interpret and respond to them. The stresses, drought, salinity, chemicals, cold and …

Mutant p53 in cancer: accumulation, gain-of-function, and therapy

X Yue, Y Zhao, Y Xu, M Zheng, Z Feng, W Hu - Journal of molecular biology, 2017 - Elsevier
Tumor suppressor p53 plays a central role in tumor suppression. p53 is the most frequently
mutated gene in human cancer, and over half of human cancers contain p53 mutations …

Heat shock signaling in land plants: from plasma membrane sensing to the transcription of small heat shock proteins

B Bourgine, A Guihur - Frontiers in plant science, 2021 - frontiersin.org
Heat stress events are major factors limiting crop productivity. During summer days, land
plants must anticipate in a timely manner upcoming mild and severe temperature. They …

The heat shock response: life on the verge of death

K Richter, M Haslbeck, J Buchner - Molecular cell, 2010 - cell.com
Organisms must survive a variety of stressful conditions, including sudden temperature
increases that damage important cellular structures and interfere with essential functions. In …

Insights into the red algae and eukaryotic evolution from the genome of Porphyra umbilicalis (Bangiophyceae, Rhodophyta)

SH Brawley, NA Blouin, E Ficko-Blean… - Proceedings of the …, 2017 - National Acad Sciences
Porphyra umbilicalis (laver) belongs to an ancient group of red algae (Bangiophyceae), is
harvested for human food, and thrives in the harsh conditions of the upper intertidal zone …

The HSP70 chaperone machinery: J proteins as drivers of functional specificity

HH Kampinga, EA Craig - Nature reviews Molecular cell biology, 2010 - nature.com
Heat shock 70 kDa proteins (HSP70s) are ubiquitous molecular chaperones that function in
a myriad of biological processes, modulating polypeptide folding, degradation and …

Noncoding translation mitigation

JS Kesner, Z Chen, P Shi, AO Aparicio, MR Murphy… - Nature, 2023 - nature.com
Translation is pervasive outside of canonical coding regions, occurring in long noncoding
RNAs, canonical untranslated regions and introns,,–, especially in ageing …

Protein homeostasis and aging: The importance of exquisite quality control

H Koga, S Kaushik, AM Cuervo - Ageing research reviews, 2011 - Elsevier
All cells count on precise mechanisms that regulate protein homeostasis to maintain a stable
and functional proteome. A progressive deterioration in the ability of cells to preserve the …