[HTML][HTML] Structure-function relationships in pulmonary surfactant membranes: from biophysics to therapy
E Lopez-Rodriguez, J Pérez-Gil - Biochimica et Biophysica Acta (BBA) …, 2014 - Elsevier
Pulmonary surfactant is an essential lipid–protein complex to maintain an operative
respiratory surface at the mammalian lungs. It reduces surface tension at the alveolar air …
respiratory surface at the mammalian lungs. It reduces surface tension at the alveolar air …
Pulmonary surfactant: A mighty thin film
F Possmayer, YY Zuo, RAW Veldhuizen… - Chemical …, 2023 - ACS Publications
Pulmonary surfactant is a critical component of lung function in healthy individuals. It
functions in part by lowering surface tension in the alveoli, thereby allowing for breathing …
functions in part by lowering surface tension in the alveoli, thereby allowing for breathing …
[HTML][HTML] Current perspectives in pulmonary surfactant—inhibition, enhancement and evaluation
Pulmonary surfactant (PS) is a complicated mixture of approximately 90% lipids and 10%
proteins. It plays an important role in maintaining normal respiratory mechanics by reducing …
proteins. It plays an important role in maintaining normal respiratory mechanics by reducing …
[HTML][HTML] Structure of pulmonary surfactant membranes and films: the role of proteins and lipid–protein interactions
J Pérez-Gil - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2008 - Elsevier
The pulmonary surfactant system constitutes an excellent example of how dynamic
membrane polymorphism governs some biological functions through specific lipid–lipid …
membrane polymorphism governs some biological functions through specific lipid–lipid …
Barrier or carrier? Pulmonary surfactant and drug delivery
To consider the lung as a target for drug delivery and to optimise strategies directed at the
pulmonary route, it is essential to consider the role of pulmonary surfactant, a thin lipid …
pulmonary route, it is essential to consider the role of pulmonary surfactant, a thin lipid …
Models using native tracheobronchial mucus in the context of pulmonary drug delivery research: composition, structure and barrier properties
BC Huck, X Murgia, S Frisch, M Hittinger… - Advanced Drug Delivery …, 2022 - Elsevier
Mucus covers all wet epithelia and acts as a protective barrier. In the airways of the lungs,
the viscoelastic mucus meshwork entraps and clears inhaled materials and efficiently …
the viscoelastic mucus meshwork entraps and clears inhaled materials and efficiently …
[HTML][HTML] Pulmonary surfactant and nanocarriers: Toxicity versus combined nanomedical applications
Pulmonary surfactant is a membrane-based lipid-protein system essential for the process of
breathing, which coats and stabilizes the whole respiratory surface and possesses …
breathing, which coats and stabilizes the whole respiratory surface and possesses …
Peptoids: bio-inspired polymers as potential pharmaceuticals
MT Dohm, R Kapoor, AE Barron - Current pharmaceutical …, 2011 - ingentaconnect.com
Peptoids are a developing class of peptide-like oligomers originally invented for drug
discovery in the early 1990s. While peptides hold great promise for therapeutic applications …
discovery in the early 1990s. While peptides hold great promise for therapeutic applications …
[HTML][HTML] Overcoming the pulmonary barrier: New insights to improve the efficiency of inhaled therapeutics
X Murgia, C de Souza Carvalho… - European Journal of …, 2014 - degruyter.com
The pulmonary route offers an exceptional, non-invasive administration site for drug
delivery. The principal characteristics that make the lungs an appealing route for drug …
delivery. The principal characteristics that make the lungs an appealing route for drug …
[HTML][HTML] Why do we have to move fluid to be able to breathe?
The ability to breathe air represents a fundamental step in vertebrate evolution that was
accompanied by several anatomical and physiological adaptations. The morphology of the …
accompanied by several anatomical and physiological adaptations. The morphology of the …