Vascular smooth muscle cells (VSMCs) have critical functions in vascular diseases.
Haemodynamic factors are important regulators of VSMC functions in vascular …

Atherosclerosis is a multi-factorial inflammatory disease and is the primary initiator of
coronary artery and cerebrovascular disease. Initially believed to be exclusively lipid-driven …

Recent findings have implicated the gut microbiota as a contributor of metabolic diseases
through the modulation of host metabolism and inflammation. Atherosclerosis is associated …

Periodontal disease has been associated with atherosclerosis, suggesting that bacteria from
the oral cavity may contribute to the development of atherosclerosis and cardiovascular …

Background and Purpose—Current Swedish guidelines recommend that carotid
endarterectomy should be performed within 14 days of a qualifying neurological event, but it …

The role of wall shear stress (WSS) in atherosclerotic plaque development is evident, but the
relation between WSS and plaque composition in advanced atherosclerosis, potentially …

Gut microbiota composition has been reported as a factor linking host metabolism with the
development of cardiovascular diseases (CVD) and intestinal immunity. Such gut microbiota …

Rupture of atherosclerotic plaques causing thrombosis is the main cause of acute coronary
syndrome and ischemic strokes. Inhibition of thrombosis is one of the important tasks …

Lipids, abundant constituents of both the vascular plaque and lipoproteins, play a pivotal
role in atherosclerosis. Mass spectrometry-based analysis of lipids, called lipidomics …

Background and aims Several studies have confirmed the presence of bacterial DNA in
atherosclerotic plaques, but its contribution to plaque stability and vulnerability is unclear. In …