Incipient and subclinical tuberculosis: a clinical review of early stages and progression of infection

PK Drain, KL Bajema, D Dowdy, K Dheda… - Clinical microbiology …, 2018 - Am Soc Microbiol
Tuberculosis (TB) is the leading infectious cause of mortality worldwide, due in part to a
limited understanding of its clinical pathogenic spectrum of infection and disease …

Xpert MTB/RIF and Xpert MTB/RIF Ultra for pulmonary tuberculosis and rifampicin resistance in adults

JS Zifodya, I Schiller, N Dendukuri… - Cochrane Database …, 2019 - cochranelibrary.com
Background Xpert MTB/RIF (Xpert MTB/RIF) and Xpert MTB/RIF Ultra (Xpert Ultra), the
newest version, are the only World Health Organization (WHO)‐recommended rapid tests …

The New Xpert MTB/RIF Ultra: Improving Detection of Mycobacterium tuberculosis and Resistance to Rifampin in an Assay Suitable for Point-of-Care Testing

S Chakravorty, AM Simmons, M Rowneki, H Parmar… - MBio, 2017 - Am Soc Microbiol
ABSTRACT The Xpert MTB/RIF assay (Xpert) is a rapid test for tuberculosis (TB) and
rifampin resistance (RIF-R) suitable for point-of-care testing. However, it has decreased …

Xpert® MTB/RIF assay for pulmonary tuberculosis and rifampicin resistance in adults

KR Steingart, I Schiller, DJ Horne, M Pai… - Cochrane database …, 2014 - cochranelibrary.com
Background Accurate, rapid detection of tuberculosis (TB) and TB drug resistance is critical
for improving patient care and decreasing TB transmission. Xpert® MTB/RIF assay is an …

Prevalence of tuberculosis in post-mortem studies of HIV-infected adults and children in resource-limited settings: a systematic review and meta-analysis

RK Gupta, SB Lucas, KL Fielding, SD Lawn - Aids, 2015 - journals.lww.com
Objectives: Tuberculosis (TB) is estimated to be the leading cause of HIV-related deaths
globally. However, since HIV-associated TB frequently remains unascertained, we …

The perfect storm: incarceration and the high-risk environment perpetuating transmission of HIV, hepatitis C virus, and tuberculosis in Eastern Europe and Central Asia

FL Altice, L Azbel, J Stone, E Brooks-Pollock… - The Lancet, 2016 - thelancet.com
Despite global reductions in HIV incidence and mortality, the 15 UNAIDS-designated
countries of Eastern Europe and Central Asia (EECA) that gained independence from the …

Feasibility, accuracy, and clinical effect of point-of-care Xpert MTB/RIF testing for tuberculosis in primary-care settings in Africa: a multicentre, randomised, controlled …

G Theron, L Zijenah, D Chanda, P Clowes, A Rachow… - The Lancet, 2014 - thelancet.com
Summary Background The Xpert MTB/RIF test for tuberculosis is being rolled out in many
countries, but evidence is lacking regarding its implementation outside laboratories, ability to …

Xpert® MTB/RIF assay: development, evaluation and implementation of a new rapid molecular diagnostic for tuberculosis and rifampicin resistance

SD Lawn, MP Nicol - Future microbiology, 2011 - Taylor & Francis
Global TB control efforts have been severely hampered by the lack of diagnostic tests that
are accurate, simple to use and can be applied at the point of clinical care. This has been …

[HTML][HTML] The biology of mycobacterium tuberculosis infection

G Delogu, M Sali, G Fadda - Mediterranean journal of hematology …, 2013 - ncbi.nlm.nih.gov
Tuberculosis (TB) still poses a major threat to mankind and during the last thirty years we
have seen a recrudescence of the disease even in countries where TB was thought to be …

Advances in tuberculosis diagnostics: the Xpert MTB/RIF assay and future prospects for a point-of-care test

SD Lawn, P Mwaba, M Bates, A Piatek… - The Lancet infectious …, 2013 - thelancet.com
Rapid progress has been made in the development of new diagnostic assays for
tuberculosis in recent years. New technologies have been developed and assessed, and …