Widespread association of the Argonaute protein AGO2 with meiotic chromatin suggests a distinct nuclear function in mammalian male reproduction

KN Griffin, BW Walters, H Li, H Wang… - Genome …, 2022 - genome.cshlp.org
Argonaute 2 (AGO2) is a ubiquitously expressed protein critical for regulation of mRNA
translation and vital to animal development. AGO2 protein is found in both cytoplasmic and …

Nuclear AGO2 promotes myocardial remodeling by activating ANKRD1 transcription in failing hearts

R Xie, S Yuan, G Hu, J Zhan, K Jin, Y Tang, J Fan… - Molecular Therapy, 2024 - cell.com
Heart failure (HF) is manifested by transcriptional and posttranscriptional reprogramming of
critical genes. Multiple studies have revealed that microRNAs could translocate into …

A nuclear role for the Argonaute protein AGO2 in mammalian gametogenesis

KN Griffin, H Li, BW Walters, H Wang, CB Kaya… - bioRxiv, 2021 - biorxiv.org
Summary Argonaute 2 (AGO2) is a ubiquitously expressed protein critical for regulation of
mRNA translation and vital to animal development. AGO2 protein is found in both …