Macrophage-targeted nanomedicine for the diagnosis and treatment of atherosclerosis
Nanotechnology could improve our understanding of the pathophysiology of atherosclerosis
and contribute to the development of novel diagnostic and therapeutic strategies to further …
and contribute to the development of novel diagnostic and therapeutic strategies to further …
Lipids and lipid derivatives for RNA delivery
RNA-based therapeutics have shown great promise in treating a broad spectrum of
diseases through various mechanisms including knockdown of pathological genes …
diseases through various mechanisms including knockdown of pathological genes …
Macrophages in atherosclerosis regression
TJ Barrett - Arteriosclerosis, thrombosis, and vascular biology, 2020 - Am Heart Assoc
Macrophages play a central role in the development of atherosclerotic cardiovascular
disease (ASCVD), which encompasses coronary artery disease, peripheral artery disease …
disease (ASCVD), which encompasses coronary artery disease, peripheral artery disease …
Nanomedicines for cardiovascular disease
BR Smith, ER Edelman - Nature Cardiovascular Research, 2023 - nature.com
The leading cause of death in the world, cardiovascular disease (CVD), remains a
formidable condition for researchers, clinicians and patients alike. CVD comprises a broad …
formidable condition for researchers, clinicians and patients alike. CVD comprises a broad …
Recent advances in nanomaterials for therapy and diagnosis for atherosclerosis
Atherosclerosis is a chronic inflammatory disease driven by lipid accumulation in arteries,
leading to narrowing and thrombosis. It affects the heart, brain, and peripheral vessels and is …
leading to narrowing and thrombosis. It affects the heart, brain, and peripheral vessels and is …
Multifunctional nanoparticle-mediated combining therapy for human diseases
X Li, X Peng, M Zoulikha, GF Boafo, KT Magar… - … and Targeted Therapy, 2024 - nature.com
Combining existing drug therapy is essential in developing new therapeutic agents in
disease prevention and treatment. In preclinical investigations, combined effect of certain …
disease prevention and treatment. In preclinical investigations, combined effect of certain …
High-density lipoprotein-mimicking nanodiscs for chemo-immunotherapy against glioblastoma multiforme
P Kadiyala, D Li, FM Nuñez, D Altshuler, R Doherty… - ACS …, 2019 - ACS Publications
Glioblastoma multiforme (GBM) is an aggressive primary brain tumor, for which there is no
cure. Treatment effectiveness for GBM has been limited due to tumor heterogeneity, an …
cure. Treatment effectiveness for GBM has been limited due to tumor heterogeneity, an …
Advanced nanomedicines for the treatment of inflammatory diseases
R Brusini, M Varna, P Couvreur - Advanced drug delivery reviews, 2020 - Elsevier
Inflammation, a common feature of many diseases, is an essential immune response that
enables survival and maintains tissue homeostasis. However, in some conditions, the …
enables survival and maintains tissue homeostasis. However, in some conditions, the …
Advances in HDL: much more than lipid transporters
S Ben-Aicha, L Badimon, G Vilahur - International Journal of Molecular …, 2020 - mdpi.com
High Density Lipoprotein (HDL) particles, beyond serving as lipid transporters and playing a
key role in reverse cholesterol transport, carry a highly variable number of proteins, micro …
key role in reverse cholesterol transport, carry a highly variable number of proteins, micro …
Targeting Theranostics of Atherosclerosis by Dual‐Responsive Nanoplatform via Photoacoustic Imaging and Three‐In‐One Integrated Lipid Management
Atherosclerosis, as a life‐threatening cardiovascular disease with chronic inflammation and
abnormal lipid enrichment, is often difficult to treat timely due to the lack of obvious …
abnormal lipid enrichment, is often difficult to treat timely due to the lack of obvious …