Cancer cachexia: more than skeletal muscle wasting
SF Schmidt, M Rohm, S Herzig, MB Diaz - Trends in cancer, 2018 - cell.com
Cancer cachexia is a multifactorial condition characterized by body weight loss that
negatively affects quality of life and survival of patients with cancer. Despite the clinical …
negatively affects quality of life and survival of patients with cancer. Despite the clinical …
The pathogenesis and treatment of cardiac atrophy in cancer cachexia
KT Murphy - American Journal of Physiology-Heart and …, 2016 - journals.physiology.org
Cancer cachexia is a multifactorial syndrome characterized by a progressive loss of skeletal
muscle mass associated with significant functional impairment. In addition to a loss of …
muscle mass associated with significant functional impairment. In addition to a loss of …
Subcutaneous Ehrlich Ascites Carcinoma mice model for studying cancer-induced cardiomyopathy
Cardiomyopathy is one of the characteristic features of cancer. In this study, we establish a
suitable model to study breast cancer-induced cardiomyopathy in mice. We used Ehrlich …
suitable model to study breast cancer-induced cardiomyopathy in mice. We used Ehrlich …
Prevention of liver cancer cachexia-induced cardiac wasting and heart failure
J Springer, A Tschirner, A Haghikia… - European heart …, 2014 - academic.oup.com
Aims Symptoms of cancer cachexia (CC) include fatigue, shortness of breath, and impaired
exercise capacity, which are also hallmark symptoms of heart failure (HF). Herein, we …
exercise capacity, which are also hallmark symptoms of heart failure (HF). Herein, we …
Establishment and characterization of a novel murine model of pancreatic cancer cachexia
KA Michaelis, X Zhu, KG Burfeind… - Journal of cachexia …, 2017 - Wiley Online Library
Background Cachexia is a complex metabolic and behavioural syndrome lacking effective
therapies. Pancreatic ductal adenocarcinoma (PDAC) is one of the most important …
therapies. Pancreatic ductal adenocarcinoma (PDAC) is one of the most important …
Cardiac muscle wasting in individuals with cancer cachexia
A Barkhudaryan, N Scherbakov, J Springer… - ESC Heart …, 2017 - Wiley Online Library
Aims Cachexia is a severe complication of cancer that adversely affects the course of the
disease and is associated with high rates of mortality. Patients with cancer manifest …
disease and is associated with high rates of mortality. Patients with cancer manifest …
Molecular pathways leading to loss of skeletal muscle mass in cancer cachexia–can findings from animal models be translated to humans?
TC Mueller, J Bachmann, O Prokopchuk, H Friess… - BMC cancer, 2016 - Springer
Background Cachexia is a multi-factorial, systemic syndrome that especially affects patients
with cancer of the gastrointestinal tract, and leads to reduced treatment response, survival …
with cancer of the gastrointestinal tract, and leads to reduced treatment response, survival …
Aerobic and resistance training dependent skeletal muscle plasticity in the colon-26 murine model of cancer cachexia
AV Khamoui, BS Park, DH Kim, MC Yeh, SL Oh… - Metabolism, 2016 - Elsevier
Purpose The appropriate mode of exercise training for cancer cachexia is not well-
established. Using the colon-26 (C26) mouse model of cancer cachexia, we defined and …
established. Using the colon-26 (C26) mouse model of cancer cachexia, we defined and …
Tumor growth increases neuroinflammation, fatigue and depressive-like behavior prior to alterations in muscle function
Cancer patients frequently suffer from fatigue, a complex syndrome associated with loss of
muscle mass, weakness, and depressed mood. Cancer-related fatigue (CRF) can be …
muscle mass, weakness, and depressed mood. Cancer-related fatigue (CRF) can be …
Concurrent evolution of cancer cachexia and heart failure: bilateral effects exist
SMR Kazemi-Bajestani, H Becher… - Journal of cachexia …, 2014 - Springer
Cancer cachexia is defined as a multifactorial syndrome of involuntary weight loss
characterized by an ongoing loss of skeletal muscle mass and progressive functional …
characterized by an ongoing loss of skeletal muscle mass and progressive functional …