Auxin Signaling | Plant Physiology | Oxford Academic Skip to Main Content Advertisement
Oxford Academic Journals Books Search Menu Information Account Menu Information …

Abstract The Rho GTPases—RHOA, RAC1 and CDC42—are small GTP binding proteins
that regulate basic biological processes such as cell locomotion, cell division and …

One of the major challenges in modern biology is to understand how the molecular
components of a living cell operate in a highly noisy environment. What are the specific …

Little is known about how neutrophils and other cells establish a single zone of actin
assembly during migration. A widespread assumption is that the leading edge prevents …

A conserved molecular machinery centered on the Cdc42 GTPase regulates cell polarity in
diverse organisms. Here we review findings from budding and fission yeasts that reveal both …

Motile eukaryotic cells polarize in response to external signals. Numerous mechanisms
have been suggested to account for this symmetry breaking and for the ensuing robust …

Cell migration is a pervasive process in many biology systems and involves protrusive
forces generated by actin polymerization, myosin dependent contractile forces, and force …

Polarization, a primary step in the response of an individual eukaryotic cell to a spatial
stimulus, has attracted numerous theoretical treatments complementing experimental …

Complex biochemical networks can be understood by identifying their principal regulatory
motifs and mode of action. We model the early phase of budding yeast cellular polarization …

Dynamic patterning of specific proteins is essential for the spatio-temporal regulation of
many important intracellular processes in prokaryotes, eukaryotes and multicellular …