Global incidence of necrotizing enterocolitis: a systematic review and meta-analysis

A Alsaied, N Islam, L Thalib - BMC pediatrics, 2020 - Springer
Abstract Background Necrotizing Enterocolitis (NEC) is a major cause of morbidity and
mortality in the Neonatal Intensive Care Unit (NICU), yet the global incidence of NEC has not …

Incidence of neonatal necrotising enterocolitis in high-income countries: a systematic review

C Battersby, T Santhalingam, K Costeloe… - Archives of Disease in …, 2018 - fn.bmj.com
Objective To conduct a systematic review of neonatal necrotising enterocolitis (NEC) rates in
high-income countries published in peer-reviewed journals. Methods We searched …

Association between antibiotic use and neonatal mortality and morbidities in very low-birth-weight infants without culture-proven sepsis or necrotizing enterocolitis

JY Ting, A Synnes, A Roberts, A Deshpandey… - JAMA …, 2016 - jamanetwork.com
Importance Excessive antibiotic use has been associated with altered bacterial colonization
and may result in antibiotic resistance, fungemia, necrotizing enterocolitis (NEC), and …

[HTML][HTML] Recent advances in understanding necrotizing enterocolitis

M Alganabi, C Lee, E Bindi, B Li, A Pierro - F1000Research, 2019 - ncbi.nlm.nih.gov
Necrotizing enterocolitis is a devastating intestinal disease affecting preterm infants. In spite
of ongoing research and advancement in neonatal care, mortality remains high, especially …

Greater mortality and morbidity in extremely preterm infants fed a diet containing cow milk protein products

SA Abrams, RJ Schanler, ML Lee… - Breastfeeding …, 2014 - liebertpub.com
Background: Provision of human milk has important implications for the health and
outcomes of extremely preterm (EP) infants. This study evaluated the effects of an exclusive …

Neonatal sepsis definitions from randomised clinical trials

R Hayes, J Hartnett, G Semova, C Murray, K Murphy… - Pediatric …, 2023 - nature.com
Introduction Neonatal sepsis is a leading cause of infant mortality worldwide with non-
specific and varied presentation. We aimed to catalogue the current definitions of neonatal …

Pathogenesis of NEC: impact of an altered intestinal microbiome

J Neu, M Pammi - Seminars in perinatology, 2017 - Elsevier
Necrotizing enterocolitis (NEC), a disease most commonly seen in preterm infants, often
presents without warning and is associated with very high mortality and morbidity. Progress …

Necrotizing enterocolitis: The intestinal microbiome, metabolome and inflammatory mediators

J Neu, M Pammi - Seminars in fetal and neonatal medicine, 2018 - Elsevier
Necrotizing enterocolitis (NEC) is a disease of preterm infants and associated with
significant mortality and morbidity. Although the pathogenesis of NEC is not clear, microbial …

Fecal microbiota transplantation (FMT) could reverse the severity of experimental necrotizing enterocolitis (NEC) via oxidative stress modulation

X Li, X Li, Q Shang, Z Gao, F Hao, H Guo… - Free Radical Biology and …, 2017 - Elsevier
Fecal microbiota transplantation (FMT) has been used successfully to treat a variety of
gastroenterological diseases. The alterations of microbiota in mouse models of necrotizing …

Practice summary of antimicrobial therapy for commonly encountered conditions in the neonatal intensive care unit: a Canadian perspective

JY Ting, J Autmizguine, MS Dunn, J Choudhury… - Frontiers in …, 2022 - frontiersin.org
Neonates are highly susceptible to infections owing to their immature cellular and humoral
immune functions, as well the need for invasive devices. There is a wide practice variation in …