Relative telomere length change in colorectal carcinoma and its association with tumor characteristics, gene expression and microsatellite instability
Simple Summary Telomeres are specialized repeat DNA sequences at the ends of each
chromosome. The primary function of telomeres is to prevent genomic instability. Telomeres …
chromosome. The primary function of telomeres is to prevent genomic instability. Telomeres …
A transcriptome and methylome study comparing tissues of early and late onset colorectal carcinoma
There is an increase in the incidence of early onset colorectal carcinoma (EOCRC). To
better understand if there is any difference in molecular pathogenesis of EOCRC and late …
better understand if there is any difference in molecular pathogenesis of EOCRC and late …
[HTML][HTML] Microsatellite Status Detection of Colorectal Cancer: Evaluation of Inconsistency between PCR and IHC
J Chen, Q Yan, J Sun, Q Wang, Y Tao, D Xiao… - Journal of …, 2023 - ncbi.nlm.nih.gov
Objective: An essential component of precision medical treatment for colorectal cancer
(CRC) is the use of microsatellite state in combination with polymerase chain reaction (PCR) …
(CRC) is the use of microsatellite state in combination with polymerase chain reaction (PCR) …
High performance methylated DNA markers for detection of colon adenocarcinoma
RAM Klein Kranenbarg, AH Vali, JNM IJzermans… - Clinical …, 2021 - Springer
Background Colon cancer (CC) is treatable if detected in its early stages. Improved CC
detection assays that are highly sensitive, specific, and available at point of care are …
detection assays that are highly sensitive, specific, and available at point of care are …
Development and validation of a new stage-specific nomogram model for predicting cancer-specific survival in patients in different stages of colon cancer: a SEER …
C Hu, F Shi, Z Zhang, L Zhang, R Liu, X Sun… - Frontiers in …, 2022 - frontiersin.org
Background The effects of laterality of the primary tumor on survival in patients in different
stages of colon cancer are contradictory. We still lack a strictly evaluated and validated …
stages of colon cancer are contradictory. We still lack a strictly evaluated and validated …
A pan-cancer analysis of the core pre-mRNA 3′ end processing factors, and their association with prognosis, tumor microenvironment, and potential targets
X Li, Y Che, X Wang, Y Zhu - Scientific Reports, 2024 - nature.com
Alternative polyadenylation (APA) is a crucial mechanism for regulating gene expression
during pre-mRNA 3′ processing. Pre-mRNA 3′ end processing factors is the main factor …
during pre-mRNA 3′ processing. Pre-mRNA 3′ end processing factors is the main factor …
[HTML][HTML] Association of KRAS Mutation and Gene Pathways in Colorectal Carcinoma: A Transcriptome- and Methylome-Wide Study and Potential Implications for …
F Jasmine, A Almazan, Y Khamkevych… - International Journal of …, 2024 - mdpi.com
Kirsten Rat Sarcoma (KRAS) is the most commonly mutated oncogene in colorectal
carcinoma (CRC). We have previously reported the interactions between microsatellite …
carcinoma (CRC). We have previously reported the interactions between microsatellite …
LncRNA WAC-AS1 expression in human tumors correlates with immune infiltration and affects prognosis
Y Wang, H Gong, Y Cao - Hereditas, 2023 - Springer
Abstract Background WAC-antisense RNA1 (WAC-AS1) is a newly identified long non-
coding RNA (lncRNA) implicated in the prognosis and development of a few types of tumors …
coding RNA (lncRNA) implicated in the prognosis and development of a few types of tumors …
Pathways Related to Colon Inflammation Are Associated with Colorectal Carcinoma: A Transcriptome-and Methylome-Wide Study
MG Kibriya, F Jasmine, J Pekow, A Munoz, C Weber… - Cancers, 2023 - mdpi.com
Simple Summary Colon cancer is one of the common cancers affecting a large number of
patients globally. In sporadic CRC, several genetic factors may play important roles such as …
patients globally. In sporadic CRC, several genetic factors may play important roles such as …
Association of Microsatellite Instability and Gene Expression Profile in Colorectal Carcinoma and Potential Implications for Therapy
MG Kibriya, F Jasmine, Y Khamkevych, M Raza… - Medicina, 2024 - mdpi.com
Background and Objective: In sporadic colorectal carcinomas (CRC), microsatellite
instability (MSI) pathways play important roles. Previously, we showed differences in DNA …
instability (MSI) pathways play important roles. Previously, we showed differences in DNA …