There is increasing appreciation that mitochondria serve cellular functions beyond oxygen
sensing and energy production. Accordingly, it has become important to explore …

Mitochondria are biosynthetic, bioenergetic, and signaling organelles which are critical for
physiological adaptations and cellular stress responses to the environment. Various …

Abstract Purpose of Review Obesity-associated difficult asthma continues to be a substantial
problem and, despite a move to address treatable traits affecting asthma morbidity and …

Mitochondria, as the powerhouse organelle of cells, are greatly involved in regulating cell
signaling pathways, including those related to the innate and acquired immune systems …

The majority of patients with severe or difficult-to-control asthma in the United States are
obese. Epidemiological studies have clearly established that obese patients tend to have …

Background Obesity increases both the risk of asthma and asthma severity and is a well-
known risk factor for insulin resistance and the metabolic syndrome (MS) in children and …

The term (bronchial) asthma describes a disorder syndrome that comprises several disease
phenotypes, all characterized by chronic inflammation in the bronchial epithelium, with a …

The ongoing coronavirus disease 2019 (COVID-19) pandemic has led to the initiation of
unprecedented research efforts to understand the pathogenesis mediated by Severe Acute …

Obesity and accompanying metabolic disease is negatively correlated with lung health yet
the exact mechanisms by which obesity affects the lung are not well characterized. Since …

Bronchial asthma is a heterogeneous disease characterised by chronic airway inflammation.
A variety of immune cells such as eosinophils, mast cells, T lymphocytes, neutrophils and …