[HTML][HTML] Benzimidazole and its derivatives: Recent Advances (2020–2022)
O Ebenezer, F Oyetunde-Joshua, OD Omotoso… - Results in …, 2023 - Elsevier
Benzimidazoles are fused heterocyclic ring systems containing two nitrogen atoms. They
have vital therapeutic significance in drug discovery. Many clinically approved drugs have …
have vital therapeutic significance in drug discovery. Many clinically approved drugs have …
The Multi‐Pharmacological Targeted Role of Indole and its Derivatives: A review
B Suliphuldevara Mathada… - …, 2023 - Wiley Online Library
Heterocycles are a privileged motif that appears as a momentous objective in medicinal
chemistry. An important class of compounds for drug discovery and design is indole and its …
chemistry. An important class of compounds for drug discovery and design is indole and its …
Molecular docking analysis and evaluation of the antimicrobial properties of the constituents of Geranium wallichianum D. Don ex Sweet from Kashmir Himalaya
Geranium wallichianum D. Don ex Sweet is a well-known medicinal plant in Kashmir
Himalya. The evidence for its modern medicinal applications remains majorly unexplored …
Himalya. The evidence for its modern medicinal applications remains majorly unexplored …
Benzimidazole hybrids as anticancer drugs: An updated review on anticancer properties, structure–activity relationship, and mechanisms of action (2019–2021)
LS Feng, WQ Su, JB Cheng, T Xiao, HZ Li… - Archiv der …, 2022 - Wiley Online Library
Cancer, characterized by a deregulation of the cell cycle which mainly results in a
progressive loss of cellular differentiation and uncontrolled cellular growth, remains a …
progressive loss of cellular differentiation and uncontrolled cellular growth, remains a …
Recent advances in the anticancer applications of benzimidazole derivatives
Cancer, one of the most deadly diseases worldwide, is still a crucial challenge to human
well‐being. Hence, the design and development of modern protocols to cure diverse kinds …
well‐being. Hence, the design and development of modern protocols to cure diverse kinds …
Synthesis, Anticancer Activity, and In Silico Modeling of Alkylsulfonyl Benzimidazole Derivatives: Unveiling Potent Bcl-2 Inhibitors for Breast Cancer
A series of alkylsulfonyl 1 H-benzo [d] imidazole derivatives were synthesized and evaluated
for anticancer activity against human breast cancer cells, MCF-7 in vitro. The cytotoxic …
for anticancer activity against human breast cancer cells, MCF-7 in vitro. The cytotoxic …
A new approach for the synthesis of bis (3-Indolyl) pyridines via a cooperative vinylogous anomeric based oxidation using ammonium acetate as a dual reagent …
H Sepehrmansourie, M Zarei… - Polycyclic Aromatic …, 2023 - Taylor & Francis
Herein, we introduced a new method for the synthesis of bis (3-indolyl) pyridines.
Accordingly, ammonium acetate was introduced as a dual reagent-catalyst role, for …
Accordingly, ammonium acetate was introduced as a dual reagent-catalyst role, for …
A Concise Review on Recent Development of Indole Derivatives for Anticancer Activities
Indole heterocycles have been considered as noteworthy associated hybrids because of
their diverse applications in organic synthesis, and coordination chemistry, as well as in the …
their diverse applications in organic synthesis, and coordination chemistry, as well as in the …
Synthesis, DFT Molecular Geometry and Anticancer Activity of Symmetrical 2,2′-(2-Oxo-1H-benzo[d]imidazole-1,3(2H)-diyl) Diacetate and Its …
To identify new candidate anticancer compounds, we here report the synthesis of
benzimidazole derivatives: diethyl 2, 2′-(2-oxo-1 H-benzo [d] imidazole-1, 3 (2 H)-diyl) …
benzimidazole derivatives: diethyl 2, 2′-(2-oxo-1 H-benzo [d] imidazole-1, 3 (2 H)-diyl) …
A Comprehensive Review on the Benzimidazole Scaffold as a Potential Nucleus for Anticancer Activity
It is common knowledge that cancer is the world's biggest cause of mortality. This has led to
the ongoing introduction and validation of new cancer therapy outcomes. Benzimidazole …
the ongoing introduction and validation of new cancer therapy outcomes. Benzimidazole …